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Resource: Dynamic dysregulation of retrotransposons in neurodegenerative diseases at the single-cell level
- Wankun Deng,
- Citu Citu,
- Andi Liu,
- and Zhongming Zhao
Genome Res. October 2024 34: 1687-1699; Published in Advance October 18, 2024, doi:10.1101/gr.279363.124
...and Nixon 2024). Throughout evolution, they have acquired multiple mutations or deletions, rendering them noninfectious and incapable of retrotransposition (Dopkins and Nixon 2024). In most HERVs, these mutations also suppress their transcriptional activity under physiological conditions, whereas several...
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Resource: Zebrafish transposable elements show extensive diversification in age, genomic distribution, and developmental expression
- Ni-Chen Chang,
- Quirze Rovira,
- Jonathan Wells,
- Cédric Feschotte,
- and Juan M. Vaquerizas
Genome Res. July 2022 32: 1408-1423; Published in Advance January 5, 2022, doi:10.1101/gr.275655.121
...-overlapping, intronic, and intergenic reads separately, both with bulk and scRNA-seq data (Kong et al. 2019; He et al. 2021; Shao and Wang 2021). In this work, we have combined Telescope, a recently developed tool to detect TE expression at single-locus resolution from bulk RNA-seq data (Bendall et al. 2019...
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