Searching journal content for articles similar to Gerdes Gyuricza et al. 32 (5): 838.

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Research: Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation
- Alejandro Martin-Trujillo,
- Paras Garg,
- Nihir Patel,
- Bharati Jadhav,
- and Andrew J. Sharp
Genome Res. February 2023 33: 184-196; Published in Advance December 28, 2022, doi:10.1101/gr.277057.122
...about sample collection can be found in a summary publications released by the PCGC (Pediatric Cardiac Genomics Consortium et al. 2013; Hoang et al. 2018). Briefly, the PCGC cohort comprises individuals aged from newborn to 47 yr (mean, 8.2 yr) diagnosed with a range of congenital heart defects...
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Research: Genome-wide gene expression regulation as a function of genotype and age in C. elegans
- Ana Viñuela,
- L. Basten Snoek,
- Joost A.G. Riksen,
- and Jan E. Kammenga
Genome Res. July 2010 20: 929-937; Published in Advance May 20, 2010, doi:10.1101/gr.102160.109
...Genome-wide gene expression regulation as a function of genotype and age in C. elegans Ana Viñuela 1 , L. Basten Snoek 1 , Joost A.G. Riksen and Jan E. Kammenga 2 Laboratory of Nematology, Wageningen University, 6708 PB Wageningen...
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LETTER: Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster
- Jian Chen,
- Xiaoying Shi,
- Ranjani Padmanabhan,
- Qiong Wang,
- Zhidan Wu,
- Susan C. Stevenson,
- Marc Hild,
- Dan Garza,
- and Hao Li
Genome Res. January 2008 18: 123-136; Published in Advance November 27, 2007, doi:10.1101/gr.6940108
...Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster Jian Chen 1 , Xiaoying Shi 1 , Ranjani Padmanabhan 1 , Qiong Wang 1 , Zhidan Wu 2 , Susan C. Stevenson 2...
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Research: Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis
- Soha N. Yazbek,
- David A. Buchner,
- Jonathan M. Geisinger,
- Lindsay C. Burrage,
- Sabrina H. Spiezio,
- Gabriel E. Zentner,
- Chang-Wen Hsieh,
- Peter C. Scacheri,
- Colleen M. Croniger,
- and Joseph H. Nadeau
Genome Res. July 2011 21: 1065-1073; Published in Advance April 19, 2011, doi:10.1101/gr.120741.111
...Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4 , regulates obesity and glucose homeostasis Soha N. Yazbek 1 , 3 , 5 , David A. Buchner 1 , 3 , 6 , Jonathan M. Geisinger 1 , Lindsay C. Burrage 1 , 7...
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Method: Aggregation of recount3 RNA-seq data improves inference of consensus and tissue-specific gene coexpression networks
- Prashanthi Ravichandran,
- Princy Parsana,
- Rebecca Keener,
- Kasper D. Hansen,
- and Alexis Battle
Genome Res. September 2025 35: 2087-2103; Published in Advance July 17, 2025, doi:10.1101/gr.280808.125
...the maintenance of cellular identity, homeostasis, and the cellular response to external stimuli are orchestrated through complex transcriptional coregulation of multiple genes (Hartwell et al. 1999; Hasty et al. 2002; Oltvai and Barabási 2002; Alon 2003). Gene coexpression networks (GCNs) are a commonly used...
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Research: Cellular age explains variation in age-related cell-to-cell transcriptome variability
- Ming Yang,
- Benjamin R. Harrison,
- and Daniel E.L. Promislow
Genome Res. November 2023 33: 1906-1916; Published in Advance November 16, 2023, doi:10.1101/gr.278144.123
..., and heart function all decline faster than cognitive and gastrointestinal function (Khan et al. 2017). Heterogeneity in aging among organs is observed not only in terms of structural and functional changes but also at the molecular level. For example, in mice, the timing and degree of age-related change...
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Perspective: Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship
- Marie A. Brunet,
- Sébastien A. Levesque,
- Darel J. Hunting,
- Alan A. Cohen,
- and Xavier Roucou
Genome Res. May 2018 28: 609-624; Published in Advance April 6, 2018, doi:10.1101/gr.230938.117
...overlapping) ORFs within mature gene transcripts. This has important consequences for the correlation of phenotypes and genotypes. Most alternative ORFs are not yet annotated because of a lack of evidence, and this absence from databases precludes their detection by standard proteomic methods, such as mass...
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LETTER: Defining the mammalian CArGome
- Qiang Sun,
- Guang Chen,
- Jeffrey W. Streb,
- Xiaochun Long,
- Yumei Yang,
- Christian J. Stoeckert, Jr.,
- and Joseph M. Miano
Genome Res. February 2006 16: 197-207; Published in Advance December 19, 2005, doi:10.1101/gr.4108706
...-factor-associated genes although the full spectrum of functional CArG elements in the genome (the CArGome) has yet to be defined. Here we describe a genome-wide screen to further define the functional mammalian CArGome. A computational approach involving comparative genomic analyses of human and mouse orthologous genes...
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Research: Functional genomics analysis of developing zebrafish and human endoderm reveals highly conserved cis-regulatory modules acting during vertebrate organogenesis
- Daniela M Riley,
- Randa Elsayed,
- Mark D Walsh,
- Simaran Johal,
- Ying Lin,
- Harry Walton,
- Till Bretschneider,
- Sascha Ott,
- and Andrew C Nelson
Genome Res. March 4, 2026 gr.280838.125; Published in Advance March 4, 2026, doi:10.1101/gr.280838.125
...development also likely acting within the nervous system. 33 Furthermore, these highly conserved CRMs are strongly enriched for binding sites of “neuro-34 pancreatic” transcription factors governing both pancreas and nervous system development, 35 potentially suggesting function across these distinct organ...
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Research: Cell-type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem cell–like cells
- Jennifer A. Urban,
- Daniel Ringwalt,
- John M. Urban,
- Wingel Xue,
- Ryan Gleason,
- Keji Zhao,
- and Xin Chen
Genome Res. January 2026 36: 83-101; Published in Advance December 10, 2025, doi:10.1101/gr.280809.125
..., Baltimore, Maryland 21218, USA; 2Howard Hughes Medical Institute, Baltimore, Maryland 21218, USA; 3Biosphere Sciences and Engineering, Carnegie Institution for Science, Baltimore, Maryland 21218, USA; 4Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda...
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