Searching journal content for articles similar to Gent et al. 23 (4): 628.

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  1. ...-directed DNA methylation (RdDM) (Matzke and Mosher 2014). We predicted that miRNA-like structures should be more highly methylated because they map more smRNAs. We further predicted that this effect should be primarily detected in the CHH context, because mCHH is more dependent on RdDM than mCG and mCHG (Law...
  2. ...the boundary between active and repressed chromatin (Gent et al. 2013; Li et al. 2015a). As reported in maize, DTT elements are often found near genes as a common target of CHH methylation (Fig. 1D; Supplemental Fig. S5). It is certainly clear that DNA methylation patterns are often unique to specific genomic...
  3. ...). Symmetric methylation can be maintained and inherited to daughter DNA strands in an RdDM-independent manner, whereas CHH methylation often requires RdDM and de novo targeting (Zemach et al. 2013). Intriguingly, two recent studies have shown how a transition from post-transcriptional to transcriptional...
  4. ...tissues in that mCHH was highest near genes (Fig. 3A; Supplemental Figs. S15, S16). Despite the -wide differences in distributions of 24-nt siRNAs in egg cell, sperm cell, and vegetative tissues, distributions of DNA methylation were similar between them, though the magnitude of methylation was variable...
  5. ..., and prefertilization ovary data from Li et al. (2020).Resetting to a canonical siRNA pattern might suggest that the newly detected siRNA loci in the zygote are targeted for CHH methylation during embryogenesis in an RdDM-dependent manner. We compared DNA methylation levels across different siRNA loci categories...
  6. ...such as CHG/CHH methylation, histone modification, or RNAi, DNA hypomethylation can lead to TE derepression. We therefore examined whether low mCG levels could be linked to TE loci expression. Indeed, members of all families of expressed TEs were significantly associated with lower mCG levels compared...
  7. ...-directed DNA methylation (RdDM) pathway, involving 24 or 21–22 nt siRNAs. Twenty-four-nucleotide siRNAs are derived from Polymerase IV (Pol IV) transcripts that are converted to dsRNAs by RNA-dependent RNA polymerase 2 (RDR2), which are then processed by DCL3. They act in canonical RdDM, primarily targeting...
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