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  1. ...in mammalian mitochondria, it does not appear to play a role in making translatable mRNAs (Mance et al. 2020). Because uncapped mRNAs may or may not be subject to circularization (Komar and Hatzoglou 2011), the model also fits with the evidence indicating that uncapped transcripts are more efficiently...
  2. ...transcriptome and proteome expression profiles, we harvested samples at 0, 1, 2, 3, 4, 6, and 88 8 hours after treatment (0 h - 8 h) in quadruplicate, and performed mRNA sequencing (RNA-89 seq) and high-resolution quantitative mass spectrometry (MS) measurement (Figure 1A). 90 Transcriptomes and proteomes were...
  3. ...mRNA stability, translation efficiency, or degradation pathways (Carpenter et al., 2014). 460 Recent single-cell transcriptomic studies have highlighted the remarkable cellular 461 heterogeneity of Atlantic salmon immune cells, particularly in the head kidney (Andresen et 462 al., 2024...
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  4. ...processing, or impair mt-mRNA degradation/turnover pathways. Effects of chimeric mtRNAs on protein translation could include the sequestration of ribosomes and tRNAs on these aberrant transcripts. Chimeric mtRNAs could also bind other mtRNA transcripts or even leak into the cytoplasm (Kim et al. 2017...
  5. ...-bound tRNA genes reside in euchromatic genomic regions, which are marked by active histone modifications, such as histone H3 lysine 4 trimethylation (H3K4me3) (White 2011; Schmitt et al. 2014; Ottenburghs et al. 2021). tRNAs represent one of the most abundant RNA types, well known for decoding mRNA...
  6. ...) and multicellular organisms (Brawand et al. 2011; Schmidt et al. 2012;Xiao et al. 2012). Such studiesmeasure and compare genomic profiles, including mRNA levels (Bergmann et al. 2003b; Tirosh et al. 2006;Wapinski et al. 2010; Brawand et al. 2011; Fowlkes et al. 2011; Rhind et al. 2011; Tirosh et al. 2011...
  7. ...contains all the major types of eukaryotic RNA genes: >1300 ( Stricklin et al. 2005 ) of these genes have been identified, including 630 tRNAs, 78 snRNAs, and 17 snoRNAs. Of the rRNA genes, the 18S, 28S, and 5.8S are transcribed separately by RNA polymerase I in the ∼55 copies of the 7.2-kb rDNA repeat...
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