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Method: Infernape uncovers cell type–specific and spatially resolved alternative polyadenylation in the brain
- Bowei Kang,
- Yalan Yang,
- Kaining Hu,
- Xiangbin Ruan,
- Yi-Lin Liu,
- Pinky Lee,
- Jasper Lee,
- Jingshu Wang,
- and Xiaochang Zhang
Genome Res. October 2023 33: 1774-1787; Published in Advance October 31, 2023, doi:10.1101/gr.277864.123
...We have developed the inferring alternative polyadenylation from scRNA-seq (Infernape) pipeline to investigate PA usage from single-cell and spatial transcriptomic data generated from the 10x Genomics platforms. In conjunction with cell-type identification (Zheng et al. 2017; Butler et al. 2018...
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Editorial: New frontiers in single-cell genomics
- Nicholas E. Navin,
- Orit Rozenblatt-Rosen,
- and Nancy R. Zhang
Genome Res. October 2021 31: ix-x; doi:10.1101/gr.276129.121
...of alternative polyadenylation from single-cell RNA-seq using scDaPars reveals cell subpopulations invisible to gene expression. Genome Res (this issue) 31: 1856–1866. doi:10.1101/gr.271346.120 ↵Heiser CN, Wang VM, Chen B, Hughey JJ, Lau KS. 2021. Automated quality control and cell identification of droplet...
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