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Fu et al. 26 (12): 1753
.
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:
Evolutionary dynamics of polyadenylation signals and their recognition strategies in protists
Marcin P. Sajek
,
Danielle Y. Bilodeau
,
Michael A. Beer
,
Emma Horton
,
Yukiko Miyamoto
,
Katrina B. Velle
,
Lars Eckmann
,
Lillian Fritz-Laylin
,
Olivia S. Rissland
,
and
Neelanjan Mukherjee
Genome Res.
October 2024
34
:
1570
-
1581
;
Published in Advance
September 26, 2024
,
doi:
10.1101/gr.279526.124
..., the poly(A) signal is an AAUAAA hexamer, but we recently found that the deeply branching eukaryote Giardia lamblia uses a distinct hexamer (AGURAA) and lacks any known auxiliary elements. Our discovery prompted us to explore the evolutionary
dynamics
of poly(A) signals and auxiliary elements...
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:
Genome-wide redistribution of 24-nt siRNAs in rice gametes
Chenxin Li
,
Hengping Xu
,
Fang-Fang Fu
,
Scott D. Russell
,
Venkatesan Sundaresan
,
and
Jonathan I. Gent
Genome Res.
February 2020
30
:
173
-
184
;
Published in Advance
January 2, 2020
,
doi:
10.1101/gr.253674.119
...the proportion of differentially methylated regions (DMRs) in the CHH context between mature WT and drm2 embryo across 24-nt siRNA loci categories (Fig. 3E).
Genome-wide
, 39% of eligible loci (loci that had sufficient coverage to be included in DMR analysis) were hypomethylated for mCHH in the drm2 embryo...
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:
Resetting of the 24-nt siRNA landscape in rice zygotes
Chenxin Li
,
Jonathan I. Gent
,
Hengping Xu
,
Hong Fu
,
Scott D. Russell
,
and
Venkatesan Sundaresan
Genome Res.
February 2022
32
:
309
-
323
;
Published in Advance
December 23, 2021
,
doi:
10.1101/gr.275981.121
...are relatively low (Anderson et al. 2017; Chen et al. 2017; Zhao et al. 2019).Along with
dynamic
changes in gene expression, epigenomic reprogramming has been observed during flowering plant reproduction. In
rice
and maize, the egg cell is ∼10 times larger than sperm in diameter and thus ∼1000 times larger than...
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:
Comparative analysis of alternative polyadenylation in
S. cerevisiae
and
S. pombe
Xiaochuan Liu
,
Mainul Hoque
,
Marc Larochelle
,
Jean-François Lemay
,
Nathan Yurko
,
James L. Manley
,
François Bachand
,
and
Bin Tian
Genome Res.
October 2017
27
:
1685
-
1695
;
Published in Advance
September 15, 2017
,
doi:
10.1101/gr.222331.117
..., Greenberg ME. 2008.
Genome-wide
analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent
polyadenylation
site selection. Neuron 60: 1022–1038. Geisberg JV, Moqtaderi Z, Fan X, Ozsolak F, Struhl K. 2014. Global analysis of mRNA isoform half-lives reveals...
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:
SWATH-MS-based proteogenomic analysis reveals the involvement of alternative splicing in poplar upon lead stress
Fu-Yuan Zhu
,
Xin Chen
,
Yu-Chen Song
,
Lydia Pui Ying Lam
,
Yuki Tobimatsu
,
Bei Gao
,
Mo-Xian Chen
,
and
Fu-Liang Cao
Genome Res.
March 2023
33
:
371
-
385
;
Published in Advance
March 24, 2023
,
doi:
10.1101/gr.277473.122
...to the different layers of the Circos plot and are ordered from outwards to inwards. 1, intron retention (IR); 2, multi-IR (MIR); 3, skipped exon (SKIP); 4, multiexon SKIP (MSKIP); 5,
alternative
exon 5′ (AE5′); 6,
alternative
exon 3′ (AE3′); 7,
alternative
transcription start (ATS); 8,
alternative
polyadenylation
...
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:
Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms
Tsung-Cheng Chang
,
Mihaela Pertea
,
Sungyul Lee
,
Steven L. Salzberg
,
and
Joshua T. Mendell
Genome Res.
September 2015
25
:
1401
-
1409
;
Published in Advance
August 19, 2015
,
doi:
10.1101/gr.193607.115
...
Genome-wide
annotation of microRNA primary transcript structures reveals novel regulatory mechanisms Tsung-Cheng Chang 1 , Mihaela Pertea 2 , Sungyul Lee 1 , Steven L. Salzberg 2 , 3 and Joshua T. Mendell 1 , 4 , 5 1...
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:
Long-read RNA sequencing reveals widespread sex-specific alternative splicing in threespine stickleback fish
Alice S. Naftaly
,
Shana Pau
,
and
Michael A. White
Genome Res.
August 2021
31
:
1486
-
1497
;
Published in Advance
June 15, 2021
,
doi:
10.1101/gr.274282.120
...al. 2007). Additional long-read sequencing of transcriptomes will help clarify how extensive
alternative
transcripts are among taxa.Sex chromosomes evolve sex-biased gene content owing to different selection pressures in males and females (
Rice
1984). The X Chromosome is transmitted two...
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:
Genome-wide identification of long noncoding natural antisense transcripts and their responses to light in
Arabidopsis
Huan Wang
,
Pil Joong Chung
,
Jun Liu
,
In-Cheol Jang
,
Michelle J. Kean
,
Jun Xu
,
and
Nam-Hai Chua
Genome Res.
March 2014
24
:
444
-
453
;
Published in Advance
January 8, 2014
,
doi:
10.1101/gr.165555.113
...
Genome-wide
identification of long noncoding natural antisense transcripts and their responses to light in Arabidopsis Huan Wang 1 , 4 , Pil Joong Chung 1 , 2 , 4 , Jun Liu 1 , In-Cheol Jang 1 , 3 , Michelle J. Kean 1 , Jun Xu...
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:
Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants
Ya-Ru Li
and
Ming-Jung Liu
Genome Res.
October 2020
30
:
1418
-
1433
;
Published in Advance
September 24, 2020
,
doi:
10.1101/gr.261834.120
...protein synthesis. Studies have uncovered a number of
alternative
translation initiation sites (TISs) in mammalian mRNAs and showed their roles in reshaping the proteome. However, the extent to which
alternative
TISs affect gene expression across plants remains largely unclear. Here, by profiling...
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:
Quantitative RNA-seq meta-analysis of alternative exon usage in
C. elegans
Nicolas J. Tourasse
,
Jonathan R.M. Millet
,
and
Denis Dupuy
Genome Res.
December 2017
27
:
2120
-
2128
;
Published in Advance
October 31, 2017
,
doi:
10.1101/gr.224626.117
...-splicing is strongly preferred when the closest exon is located either ∼50 or ∼100 nucleotides (nt) upstream of the acceptor site, thus confirming and refining the previously reported observations (Allen et al. 2011).
Genome-wide
quantitative visualization of differential exon usageFor each C. elegans gene, we...
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