Searching journal content for articles similar to Fritsch et al. 22 (11): 2208.

Displaying results 1-7 of 7
For checked items
  1. Research: Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data
    • Pieter Spealman,
    • Armaghan W. Naik,
    • Gemma E. May,
    • Scott Kuersten,
    • Lindsay Freeberg,
    • Robert F. Murphy,
    • and Joel McManus
    Genome Res. February 2018 28: 214-222; Published in Advance December 18, 2017, doi:10.1101/gr.221507.117
    ...in transcript leaders (5′ UTRs), are potent cis-acting regulators of translation and mRNA turnover. Recent -wide ribosome profiling studies suggest that thousands of uORFs initiate with non-AUG start codons. Although intriguing, these non-AUG uORF predictions have been made without statistical control...
    OPEN ACCESS ARTICLE
  2. Method: Long-read Ribo-STAMP simultaneously measures transcription and translation with isoform resolution
    • Pratibha Jagannatha,
    • Alexandra T. Tankka,
    • Daniel A. Lorenz,
    • Tao Yu,
    • Brian A. Yee,
    • Kristopher W. Brannan,
    • Cathy J. Zhou,
    • Jason G. Underwood,
    • and Gene W. Yeo
    Genome Res. November 2024 34: 2012-2024; Published in Advance June 21, 2024, doi:10.1101/gr.279176.124
    ...profiles obtained with long-read and short-read Ribo-STAMP. We show that LR-Ribo-STAMP successfully profiles translation of mRNA isoforms and links regulatory features, such as upstream open reading frames (uORFs), to translation measurements. We apply LR-Ribo-STAMP to discovering translational differences...
    OPEN ACCESS ARTICLE
  3. Research: Evolution at two levels of gene expression in yeast
    • Carlo G. Artieri and
    • Hunter B. Fraser
    Genome Res. March 2014 24: 411-421; Published in Advance December 6, 2013, doi:10.1101/gr.165522.113
    ...open reading frames (uORFs) in the 59UTRs of genes may regulate translational efficiency (Ingolia et al. 2009; Brar et al. 2012; Pelechano et al. 2013), however, we find no evidence that they play a significant role in explaining cis-regulatory divergence in translation between these species...
  4. Research: Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants
    • Ya-Ru Li and
    • Ming-Jung Liu
    Genome Res. October 2020 30: 1418-1433; Published in Advance September 24, 2020, doi:10.1101/gr.261834.120
    .... On the other hand, mORF translation would be favored in situations in which the uTIS of a separate ORF is bypassed via leaky scanning, or when the remaining 40S ribosomes, which complete the translation of separate uORFs, reinitiate at downstream start sites. Thus, we evaluated the respective contributions...
  5. Resource: A platform for curated products from novel open reading frames prompts reinterpretation of disease variants
    • Matthew D.C. Neville,
    • Robin Kohze,
    • Chaitanya Erady,
    • Narendra Meena,
    • Matthew Hayden,
    • David N. Cooper,
    • Matthew Mort,
    • and Sudhakaran Prabakaran
    Genome Res. February 2021 31: 327-336; Published in Advance January 19, 2021, doi:10.1101/gr.263202.120
    ...for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. Genome Res 22: 2208–2218. doi:10.1101/gr.139568.112 ↵Gao X, Wan J, Liu B, Ma M, Shen B, Qian S-B. 2015. Quantitative profiling of initiating ribosomes in vivo. Nat Methods 12: 147–153. doi:10.1038/nmeth.3208 ↵Gazal S...
  6. Perspective: Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship
    • Marie A. Brunet,
    • Sébastien A. Levesque,
    • Darel J. Hunting,
    • Alan A. Cohen,
    • and Xavier Roucou
    Genome Res. May 2018 28: 609-624; Published in Advance April 6, 2018, doi:10.1101/gr.230938.117
    ...(cardiomyopathy, nephropathy, and retinopathy). Blue arrows represent inhibitory relationships, pathways involved in diabetic complications are highlighted in green. FAO: fatty acid oxidation; PM: plasma membrane; lncRNA: long non-coding RNA; Mito: mitochondrial. (B) SLC35A4 and its uORF-encoded protein, alt...
    OPEN ACCESS ARTICLE
  7. Research: Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans
    • Dale Muzzey,
    • Gavin Sherlock,
    • and Jonathan S. Weissman
    Genome Res. June 2014 24: 963-973; Published in Advance April 14, 2014, doi:10.1101/gr.166322.113
    ...and find that SNP location and predicted mRNA-structure stability are associated with translational ASE in cis . Since this analysis probes more than 4000 allelic pairs spanning a broad range of variations, our data provide a genome-wide view into the relative impact of cis elements that regulate...
For checked items

Search Results

New Search

Modify Results

Citation format:
Results / page:
Results order:

This search

  • Alert me when new articles matching this search are published
  • Download all citations on this page to my citation manager

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research