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  1. ...absolute log2 cis ratio = 0.325 for translation and 0.288 for mRNA abundance; Kruskal–Wallis P = 0.009). This suggests that translation efficiency may be of comparable importance to mRNA abundance in the evolution of protein production rates in yeast. Among those orthologs with significant cis-regulatory...
  2. .... Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity. Genome Res 22: 1930–1939. Fridlyand LE, Philipson LH. 2006. Cold climate genes and the prevalence of type 2 diabetes mellitus. Med Hypoth 67: 1034–1041. Ge B, PokholokDK, KwanT,Grundberg E,Morcos L, VerlaanDJ, Le J, KokaV, Lam KC...
  3. ...-binding transcription factor and its cis -regulatory site have occurred in compensatory fashion. As a model of transcriptional network evolution, we examined the yeast AP-1 (yAP-1) family, which, with a total of eight members, is one of the largest paralogous TF families in S. cerevisiae ( Fernandes et al. 1997...
  4. ...with the evolution of gene expression variation within these regions (Tung et al. 2009; Zhang and Borevitz 2009). Associationmapping of ASE traits is expected to reveal true cis regulatory variation (Pastinen and Hudson 2004). Trait variance, however, could be high when many rare regulatory alleles are present...
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