Searching journal content for articles similar to Foroozandeh Shahraki et al. 34 (3): 469.

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  1. ...University, Stanford, CA 94305, United States Abstract The fourth and final phase of the ENCODE consortium has newly profiled epigenetic activity in hundreds of human tissues. Chromatin state annotations created by segmentation and annotation (SAGA) methods, such as Segway, have emerged as the predominant...
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  2. ...of genomic architectural stripes from Hi-C or Micro-C chromatin contact maps, that relies on robust image processing techniques and rigorous statistical tests for enrichment. Quagga outperforms other stripe detection methods in accuracy and is highly versatile, working with Hi-C, Micro-C, and other chromatin...
  3. ...predict the directionality of change in chromatin accessibility between the reference and variant alleles across all SNVs. All models outperformed the state-of-the-art method ChromBPNet (Pampari et al. 2024) and the random baseline, where for each SNV, a value of 0 or 1 was randomly assigned according...
  4. ...Highly accurate reference and method selection for universal cross–data set cell type annotation with CAMUS Qunlun Shen1,2, Shuqin Zhang1,3 and Shihua Zhang2,4,5 1School of Mathematical Sciences, Fudan University, Shanghai 200433, China; 2State Key Laboratory of Mathematical Sciences, Academy...
  5. ..., Barnett-Itzhaki Z, Jaitin D, Amann-Zalcenstein D, Lara-Astiaso D, Amit I. 2013. High-throughput chromatin immunoprecipitation for -wide mapping of in vivo protein-DNA interactions and epigenomic states. Nat Protoc 8: 539–554. doi:10.1038/nprot.2013.023 ↵Bolger AM, Lohse M, Usadel B. 2014. Trimmomatic...
  6. ...mutant with respect to a fixed yet robust control, we computed a baseline of chromatin occupancy by merging every mutant's MNase-seq profile and subsampling to the same total mapped reads of an individual sample (see Methods). The chromatin profile of this baseline control is highly similar...
  7. .... Finally, we determine cell-type-specific replication timing profiles, integrating our in vivo data sets with published data using cultured cell lines. Our results reveal that GSC-like cells display a distinct replication program, compared with somatic lineages, that aligns with chromatin state differences...
  8. ...and inactive ERBS did (Fig. 1G).To assess the correlation between STARR-seq-based ERBS annotation and enhancer activity within the native chromatin context, we analyzed GRO-seq signal (GEO; GSE27463) (Hah et al. 2011) at ERBS following E2 stimulation, as enhancer transcription is a well-established readout...
  9. ...responses. Anemia stress-dependent transcriptional regulation can be useful for developing clinical strategies to regenerate RBCs in chronic conditions. SNP regions annotated for associations to specific hematologic traits within anemia-sensitive chromatin accessible regions may represent new genetic...
  10. ..., chromatin accessibility in Bacteriovorax positively correlates with gene expression. Mapping active transcription through single-strand DNA (ssDNA) profiling revealed that unlike in yeast, but similar to the state of mammalian and fly promoters, Bacteriovorax promoters exhibit very strong polymerase pausing...
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