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Research: Nucleosome repositioning in chronic lymphocytic leukemia
- Kristan V. Piroeva,
- Charlotte McDonald,
- Charalampos Xanthopoulos,
- Chelsea Fox,
- Christopher T. Clarkson,
- Jan-Philipp Mallm,
- Yevhen Vainshtein,
- Luminita Ruje,
- Lara C. Klett,
- Stephan Stilgenbauer,
- Daniel Mertens,
- Efterpi Kostareli,
- Karsten Rippe,
- and Vladimir B. Teif
Genome Res. October 2023 33: 1649-1661; Published in Advance September 12, 2023, doi:10.1101/gr.277298.122
...healthy donors or CLL patients stratified into IGHV-mutated (M-CLL) or unmutated (U-CLL). These maps were integrated with data from WGBS, ATAC-seq, ChIP-seq of transcription factors (TFs) and six histone modifications, Hi-C, and RNA-seq to dissect molecular mechanisms of nucleosome repositioning. (B...
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Research: Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution
- Justyna A. Resztak,
- Julong Wei,
- Samuele Zilioli,
- Edward Sendler,
- Adnan Alazizi,
- Henriette E. Mair-Meijers,
- Peijun Wu,
- Xiaoquan Wen,
- Richard B. Slatcher,
- Xiang Zhou,
- Francesca Luca,
- and Roger Pique-Regi
Genome Res. June 2023 33: 839-856; Published in Advance July 13, 2023, doi:10.1101/gr.276765.122
...-mediated signaling, type I IFN signaling, and innate immune response (Supplemental Fig. S18). We also identified several pathways that only appeared to be enriched in DVGs, including ribosome, translation, mRNA catabolic process, protein localization to the ER, and protein targeting to the membrane and to the ER...
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