Searching journal content for articles similar to Fehniger et al. 20 (11): 1590.

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  1. Research: Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity
    • Stacia K. Wyman,
    • Emily C. Knouf,
    • Rachael K. Parkin,
    • Brian R. Fritz,
    • Daniel W. Lin,
    • Lucas M. Dennis,
    • Michael A. Krouse,
    • Philippa J. Webster,
    • and Muneesh Tewari
    Genome Res. September 2011 21: 1450-1461; Published in Advance August 3, 2011, doi:10.1101/gr.118059.110
    ..., Washington 98108, USA; 6NanoString Technologies, Seattle, Washington 98109, USA; 7Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA; 8Department of Medicine, University of Washington, Seattle, Washington 98195, USA Modification of microRNA sequences by the 39...
  2. Method: Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi
    • Trine I. Jensen,
    • Nanna S. Mikkelsen,
    • Zongliang Gao,
    • Johannes Foßelteder,
    • Gabriel Pabst,
    • Esben Axelgaard,
    • Anders Laustsen,
    • Saskia König,
    • Andreas Reinisch,
    • and Rasmus O. Bak
    Genome Res. November 2021 31: 2120-2130; Published in Advance August 18, 2021, doi:10.1101/gr.275607.121
    ...translation rates through microRNAs or mRNA-binding regulatory proteins may respond differently to CRISPRa/i, and feedback mechanisms that control gene expression may also impact the efficiency and dynamics of CRISPRa/i. Future studies should address these questions and why some genes are apparently...
  3. PERSPECTIVE: Comparing the human and chimpanzee genomes: Searching for needles in a haystack
    • Ajit Varki and
    • Tasha K. Altheide
    Genome Res. December 2005 15: 1746-1758; doi:10.1101/gr.3737405
    ...sequence differences from consideration, while simultaneously identifying potential targets of opportunity. Meanwhile, candidate gene approaches can be based on such genomic surveys, on genes that may contribute to known differences in phenotypes or disease incidence/severity, or on mutations in the human...
  4. Research: Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression
    • Runsheng Li,
    • Xiaoliang Ren,
    • Yu Bi,
    • Vincy Wing Sze Ho,
    • Chia-Ling Hsieh,
    • Amanda Young,
    • Zhihong Zhang,
    • Tingting Lin,
    • Yanmei Zhao,
    • Long Miao,
    • Peter Sarkies,
    • and Zhongying Zhao
    Genome Res. September 2016 26: 1219-1232; Published in Advance May 18, 2016, doi:10.1101/gr.204479.116
    ...with three replicates each. All RNA reads were mapped against annotated coding sequences in C. briggsae (AF16) (Harris et al. 2014). The reads were also de novo assembled into transcripts using Trinity (Haas et al. 2013) for the purpose of small RNA mapping as detailed below. We identified a total of 574...
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