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  1. ...offers a powerful route to untangle this complexity, comprehensive data sets in ducks remain scarce. Meanwhile, the contributions of peripheral systems beyond neuroendocrine regulation on poultry egg production are still largely unexplored. Here, we generate 979 RNA-seq samples from the liver, ovary...
  2. ...a key component of missing heritability and provides a novel paradigm to untangle the genetic architecture of complex disorders.Recent human population growth has led to a rapid increase in the load of rare variants affecting functionally important regions of the (Coventry et al. 2010; Keinan and Clark...
  3. ...studies and highlighted how this orthogonal approach can prioritize candidate genes. Untangling the genetic, epigenetic, and environmental mechanisms that govern allele-specific gene regulation is crucial to improving our ability to predict phenotypes from genotypes.ResultsPartitioning allele...
  4. ...of connectivity may be different if different sets of expression data are used.) This suggests a control hierarchy in which these basic processes are central to the orchestration of cellular behavior. In related work, however, it has been shown that many functional modules that are coexpressed in S. cerevisiae...
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