Searching journal content for articles similar to Fan et al. 35 (10): 2173.

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  1. Research: Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation
    • Alejandro Martin-Trujillo,
    • Paras Garg,
    • Nihir Patel,
    • Bharati Jadhav,
    • and Andrew J. Sharp
    Genome Res. February 2023 33: 184-196; Published in Advance December 28, 2022, doi:10.1101/gr.277057.122
    ...promoter region (Fig. 5), respectively. This association is consistent with the inverse correlation between DNA methylation and transcriptional activity at promoter regions. Additional examples are included in Supplemental Figure S11.View larger version: In this window In a new window Figure 5. STR-directed...
  2. Research: DNA methylation contributes to natural human variation
    • Holger Heyn,
    • Sebastian Moran,
    • Irene Hernando-Herraez,
    • Sergi Sayols,
    • Antonio Gomez,
    • Juan Sandoval,
    • Dave Monk,
    • Kenichiro Hata,
    • Tomas Marques-Bonet,
    • Liewei Wang,
    • and Manel Esteller
    Genome Res. September 2013 23: 1363-1372; Published in Advance August 1, 2013, doi:10.1101/gr.154187.112
    ..., intragenic methylation has been linked to transcriptional and splicing activities ( Jones 2012), suggesting a sophisticated regulatory potential for this epigenetic modification. DNA methylation levels are closely related to the genomic context, with CpG-rich regions (CpG islands) located in the 59 endof...
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  3. Resource: Genetic features and genomic targets of human KRAB-zinc finger proteins
    • Jonas de Tribolet-Hardy,
    • Christian W. Thorball,
    • Romain Forey,
    • Evarist Planet,
    • Julien Duc,
    • Alexandre Coudray,
    • Bara Khubieh,
    • Sandra Offner,
    • Cyril Pulver,
    • Jacques Fellay,
    • Michael Imbeault,
    • Priscilla Turelli,
    • and Didier Trono
    Genome Res. August 2023 33: 1409-1423; Published in Advance September 20, 2023, doi:10.1101/gr.277722.123
    ...was primarily because of LoF variants found in the last 5% of the canonical transcript. Because genomic sequencing methods can yield variable coverage of genetic regions, especially when it comes to exome sequencing that is dependent on the capture of previously annotated protein-coding genes, we excluded all...
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  4. PERSPECTIVE: Raising the estimate of functional human sequences
    • Michael Pheasant and
    • John S. Mattick
    Genome Res. September 2007 17: 1245-1253; Published in Advance August 9, 2007, doi:10.1101/gr.6406307
    ...RNAs in the control of chromatin architecture and epigenetic memory ( Andersen and Panning 2003 ; Bernstein and Allis 2005 ; Sanchez-Elsner et al. 2006 ; Schmitt and Paro 2006 ; Rinn et al. 2007 ), transcription ( Janowski et al. 2005 ; Goodrich and Kugel 2006 ; Kim et al. 2006 ; Li et al. 2006...
  5. Perspective: Constructing genomic maps of positive selection in humans: Where do we go from here?
    • Joshua M. Akey
    Genome Res. May 2009 19: 711-722; doi:10.1101/gr.086652.108
    ..., it will also be important to incorporate background selection (the effect of purifying selection on linked patterns of variation) (Charlesworth et al. 1993; Reed et al. 2005) into drift and draft models to better understand the causes and consequences of genomic patterns of human genetic variation. From a more...
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