Searching journal content for articles similar to Falb et al. 15 (10): 1336.

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  1. ...the new s, we show that gars have the slowest rates of genomic structural and sequence evolution of all vertebrates. In species of the two living gar genera Atractosteus and Lepisosteus, 83.35% of the s remain identical even though they diverged over 100 million years ago. Genome size variation among gars...
  2. ...deletion frequency of RE1–3. However, the genomic complexity and redundancy of the MYC locus make definitive conclusions challenging.Collectively, these observations indicate that the MYC locus has not only been amplified but also inserted into a transcriptionally active region of Chromosome 10 in C1 cells...
  3. ...basis of desiccation tolerance in nematodes Genome Research 7 www..org Discussion The desiccation tolerance mechanism of nematodes has become a primary focus among biologists. Their ability to survive for a long time in extreme drought conditions has also become an important reference value...
  4. ....Cytosine methylation plays a critical role in genomic imprinting, gene regulation, X-Chromosome inactivation (XCI), cellular differentiation, aging, and tumorigenesis. Cells have an extensive system of proteins that establish these methylation patterns through de novo methylation or demethylation, copy methylation...
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  5. ...as macrosynteny, is seen between bilaterian phyla as divergent as Chordata, Echinodermata, Mollusca, and Nemertea. Here, we report a unique pattern of evolution in Bryozoa, an understudied phylum of colonial invertebrates. Using comparative genomics, we reconstruct the chromosomal evolutionary history of five...
  6. ...the N2-derived strain VC2010. Moreover, genetically divergent versions of N2 have arisen over decades of research and hindered reproducibility of C. elegans genetics and genomics. Here we provide a 106.4 Mb gap-free, telomere-to-telomere assembly of C. elegans, generated from CGC1, an isogenic...
  7. ..., Spanish National Research Council, Paterna 46980, Spain; 2Department of Computer Science, Universitat de València, Valencia 46100, Spain; 3Department of Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, 10315 Berlin, Germany; 4Berlin Center for Genomics in Biodiversity Research...
  8. ...of bioinformatics tools and resources to interrogate s for evolutionary patterns and features of biomedical interest. But even as s became available for other model organisms such as mouse (Mus musculus) (Mouse Genome Sequencing Consortium et al. 2002) and rhesus macaque (Macaca mulatta) (Rhesus Macaque Genome...
  9. ...@tamu.edu, jje@uci.eduAbstractMany essential functions of organisms are encoded in highly repetitive genomic regions, including histones involved in DNA packaging, centromeres that are core components of chromosome segregation, ribosomal RNA comprising the protein translation machinery, telomeres that ensure...
  10. ...to UV mutagenesis. However, the impact of genomic context and chromatin architecture on CPD deamination rates in cells remains poorly understood. Here, we develop a method known as dCPD-seq to map deaminated CPDs (dCPDs) across the of repair-deficient yeast cells at single-nucleotide resolution. Our d...
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