Searching journal content for articles similar to Errbii et al. 34 (6): 863.

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  1. .... 2000), beetles (Keller et al. 2011), and possibly also mole rats (Reeve et al. 1990). In concert, these traits further act to reduce effective population sizes, and this is predicted to have negative consequences for population genetic diversity and the efficacy of selection through elevated genetic...
  2. ...provides novel insights into the genomic regulatory landscape underlying antiviral 33 immunity in a farmed fish with a complex . 34 Introduction 35 The innate immune response to viral infection, which is mainly based on the type I interferon 36 (type I IFN) pathway is crucial to both disease progression...
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  3. ...), or other regulatory elements, and constitute a substantial portion of lincRNAs (Khorkova et al. 2015; Choudhary et al. 2023). Despite their potential importance, the transcriptomic landscape and clinical relevance of TE-derived elements in PAAD remain poorly characterized, partly due to limited sample...
  4. ...OR repertoire expansion, we investigated the genomic context of clonal raider ant ORs and compared this to the remaining clonal raider ant genes. It has previously been reported that, in the ant Cardiocondyla obscurior, ORs are enriched in areas of high transposable element density (“TE islands”) (Schrader et...
  5. ...(Fig. 6E). These findings track accessibility during the early establishment and late resolution of a regeneration-dependent transcriptome in RBC precursors. Chromatin accessibility and transcriptional landscapes can be used to define mechanisms of hematopoietic differentiation within distinct...
  6. ...in cancer. In this study, we characterized the TE transcriptomic landscape using long-read RNA-seq and short-read RNA-seq in three cancer cell lines varying only in TP53 genetic status. To identify transcripts that use TEs as potential promoters, we developed a computational pipeline, TEProf3...
  7. ..., development, virulence, and stress response in F. graminearumTo determine if F. graminearum Set2 and Ash1 possess H3K36 methyltransferase activity, we heterologously expressed and purified them in Escherichia coli for in vitro enzyme assays. A recombinant H3K36 peptide, devoid of pre-existing histone...
  8. ...landscape and the rapid de novo origin of a dosage compensation system.Complete dosage compensation mechanisms have evolved in some organisms with highly diverged sex chromosomes to ameliorate the negative effects of haploinsuffiency (Ohno 1967; Bachtrog 2013). These complex mechanisms act across...
  9. ..., highlighting the importance of intercellular miRNA heterogeneity.In summary, although several studies have profiled miRNAs and their targets in single cells, there is a paucity of systematic and transcriptome-wide studies in individual mESCs. We here outline the landscape of miRNA and target expression...
  10. ...manipulation of RNA modifications has been leveraged in cancer immunotherapies. An exhaustive account of all studies related to epitranscriptomics or immunity is outside the scope of this review; however, our goal is to provide a landscape view of research being conducted at the intersection of these exciting...
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