Searching journal content for articles similar to Enikanolaiye et al. 30 (4): 540.

Displaying results 1-10 of 6118

For checked items

view abstracts
download to citation manager

Select this article
Resource: A systems view on DNA damage response kinetics in Tetrahymena
- Emily Nischwitz,
- Vivien A.C. Schoonenberg,
- Rachel Mullner,
- Albert Fradera-Sola,
- Susanne Zimbelmann,
- Joshua J. Smith,
- and Falk Butter
Genome Res. January 28, 2026 ; Published in Advance January 28, 2026, doi:10.1101/gr.281000.125
...:10.1177/106002808201600602 Fayyad N, Kobaisi F, Beal D, Mahfouf W, Ged C, Morice-Picard F, FayyadKazan M, Fayyad-Kazan H, Badran B, Rezvani HR, et al. 2020. Xeroderma pigmentosum C (XPC) mutations in primary fibroblasts impair base excision repair pathway and increase oxidative DNA damage. Front...
Select this article
Research: Long-read DNA and cDNA sequencing identify cancer-predisposing deep intronic variation in tumor-suppressor genes
- Suleyman Gulsuner,
- Amal AbuRayyan,
- Jessica B. Mandell,
- Ming K. Lee,
- Greta V. Bernier,
- Barbara M. Norquist,
- Sarah B. Pierce,
- Mary-Claire King,
- and Tom Walsh
Genome Res. November 2024 34: 1825-1831; Published in Advance September 13, 2024, doi:10.1101/gr.279158.124
...deep intronic variants for families severely affected with breast, ovarian, pancreatic, and/or metastatic prostate cancer, but with no causal variant identified by any previous genomic or cDNA-based approach. For 10 tumor-suppressor genes, we used multiplexed adaptive sampling long-read DNA sequencing...
Select this article
Research: Transcriptional modulation unique to vulnerable motor neurons predicts ALS across species and SOD1 mutations
- Irene Mei,
- Susanne Nichterwitz,
- Melanie Leboeuf,
- Jik Nijssen,
- Isadora Lenoel,
- Dirk Repsilber,
- Christian S. Lobsiger,
- and Eva Hedlund
Genome Res. September 2025 35: 1975-1991; Published in Advance July 17, 2025, doi:10.1101/gr.279501.124
...; Shadrach et al. 2021) has revealed a response to DNA damage and cell injury as well as activation of compensatory regeneration.So far no comprehensive analysis has been conducted to dissect how vulnerable versus resilient neurons respond to ALS over time. We reasoned that an analysis of how differentially...
OPEN ACCESS ARTICLE
Select this article
Method: A novel multislice framework for precision 3D spatial domain reconstruction and disease pathology analysis
- Daijun Zhang,
- Ren Qi,
- Xun Lan,
- and Bin Liu
Genome Res. August 2025 35: 1794-1808; Published in Advance July 14, 2025, doi:10.1101/gr.280281.124
...as a multislice joint analysis framework featuring a precorrection mechanism that enables the precise identification of complex spatial domains, advancing disease pathology insights. STMSC assumes that precise three-dimensional (3D) reconstruction is essential for an in-depth investigation of tissue components...
Select this article
Research: The rate and spectrum of new mutations in mice inferred by long-read sequencing
- Eugenio López-Cortegano,
- Jobran Chebib,
- Anika Jonas,
- Anastasia Vock,
- Sven Künzel,
- Peter D. Keightley,
- and Diethard Tautz
Genome Res. January 2025 35: 43-54; Published in Advance December 2, 2024, doi:10.1101/gr.279982.124
...and expansions were <1 kb, we observed a single instance of an expansion of a ∼3 kb TCTTCT satellite into a higher-order repeat, possibly >100 kb (Supplemental Fig. S8). Although DNA strand slippage during the polymerization reaction is commonly implicated in short tandem repeat mutations (Schlötterer and Tautz...
OPEN ACCESS ARTICLE
Select this article
Research: Modest increase in the de novo single-nucleotide mutation rate in house mice born by assisted reproduction
- Laura Blanco-Berdugo,
- Alexis Garretson,
- and Beth L. Dumont
Genome Res. January 2026 36: 50-60; Published in Advance November 13, 2025, doi:10.1101/gr.281180.125
....5%–56%) increase in the dnSNV rate with ART compared with naturally conceived mice (P = 0.017). Analysis of the dnSNV mutation spectrum identifies signatures attributable to germline DNA repair activity but reveals no differentially enriched signatures between cohorts. We observe no enrichment of dn...
Select this article
Research: Chimeric mitochondrial RNA transcripts predict mitochondrial genome deletion mutations in mitochondrial genetic diseases and aging
- Amy R. Vandiver,
- Allen Herbst,
- Paul Stothard,
- and Jonathan Wanagat
Genome Res. January 2025 35: 55-65; Published in Advance November 27, 2024, doi:10.1101/gr.279072.124
...to mitochondrial function, demonstrating the utility of these events as metrics of age-induced metabolic change. Mapping and quantitation of chimeric mitochondrial RNAs provide an accessible, orthogonal approach to DNA-based mutation assays, offer a potential method for identifying mitochondrial pathology...
Select this article
Research: Mendelian randomization analyses implicate biogenesis of translation machinery in human aging
- Sara Javidnia,
- Stephen Cranwell,
- Stefanie H. Mueller,
- Colin Selman,
- Jennifer M.A. Tullet,
- Karoline Kuchenbaecker,
- and Nazif Alic
Genome Res. February 2022 32: 258-265; Published in Advance January 25, 2022, doi:10.1101/gr.275636.121
...); and reduced hepatic protein synthesis is observed in long-lived mouse models (Thompson et al. 2016), whereas rDNA transcription by Pol I appears pivotal in the aging of skeletal muscle (Kirby et al. 2015). Each of the three tissues plays an important role in whole-animal metabolism. Although the link between...
OPEN ACCESS ARTICLE
Select this article
Research: Colibactin leads to a bacteria-specific mutation pattern and self-inflicted DNA damage
- Emily Lowry,
- Yiqing Wang,
- Tal Dagan,
- and Amir Mitchell
Genome Res. August 2024 34: 1154-1164; Published in Advance August 16, 2024, doi:10.1101/gr.279517.124
...the DNA damage response. Moreover, within the DNA damage response, we primarily detected genes involved in homologous recombination but only one gene linked to nucleotide excision repair.Colibactin induces a specific mutational signatureColibactin-induced damage leads to a specific mutational signature...
OPEN ACCESS ARTICLE
Select this article
Method: High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND
- Kehan Lang,
- Chenyang Jia,
- Siyu Li,
- Yi Guo,
- Dingjun Hu,
- and Shengquan Chen
Genome Res. April 2026 36: 769-784; Published in Advance March 26, 2026, doi:10.1101/gr.281350.125
...of one modality from another. However, existing methods for cross-modality translation between single-cell RNA sequencing (scRNA-seq) and single-cell DNA methylation (scDNAm) data face limitations, including unidirectionality, inadequate modeling of context-specific DNA methylation...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Enikanolaiye et al. 30 (4): 540.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: