Searching journal content for articles similar to Emerson et al. 20 (6): 826.

Displaying results 1-10 of 441

For checked items

view abstracts
download to citation manager

Select this article
Research: Natural diversity of telomere length distributions across 100 Saccharomyces cerevisiae strains
- Clotilde Garrido,
- Cintia Gómez-Muñoz,
- Etienne Kornobis,
- Nicolas Agier,
- Oana Ilioaia,
- Gilles Fischer,
- and Zhou Xu
Genome Res. March 2026 36: 522-533; Published in Advance January 16, 2026, doi:10.1101/gr.281132.125
...at a chromosome extremity is associated with shorter telomeres in cis, but (2) the overall Y′ element content in a strain correlates with longer telomeres. Finally, we show that the length of the shortest telomeres remains relatively constant across strains, suggesting a selective constraint at the species level...
Select this article
Research: Common cis-regulatory variation modifies the penetrance of pathogenic SHROOM3 variants in craniofacial microsomia
- Hao Zhu,
- Jiao Zhang,
- Soumya Rao,
- Matthew D. Durbin,
- Ying Li,
- Ruirui Lang,
- Jiqiang Liu,
- Baichuan Xiao,
- Hailin Shan,
- Ziqiu Meng,
- Jinmo Wang,
- Xiaokai Tang,
- Zhenni Shi,
- Liza L. Cox,
- Shouqin Zhao,
- Stephanie M. Ware,
- Tiong Y. Tan,
- Michelle de Silva,
- Lyndon Gallacher,
- Ting Liu,
- Jie Mi,
- Changqing Zeng,
- Hou-Feng Zheng,
- Qingguo Zhang,
- Stylianos E. Antonarakis,
- Timothy C. Cox,
- and Yong-Biao Zhang
Genome Res. May 2025 35: 1065-1079; Published in Advance April 15, 2025, doi:10.1101/gr.280047.124
...). Multiple factors affect the penetrance of P/LP variants, including genetic variants such as eQTLs regulating the expression of the trans-alleles, cis regulatory variation (cis eQTLs), genetic modifiers unlinked with the causative gene, polygenic risk, imprinting, epigenetic regulation, and environmental...
Select this article
Research: The origin and evolution of a distinct mechanism of transcription initiation in yeasts
- Zhaolian Lu and
- Zhenguo Lin
Genome Res. January 2021 31: 51-63; Published in Advance November 20, 2020, doi:10.1101/gr.264325.120
...). However, yeasts are known for their scarcity in active transposable elements (Bleykasten-Grosshans and Neuvéglise 2011). We speculate that evolutionary innovations in trans- or cis-regulatory factors probably play a more important role in the birth of new TSS in yeasts.Another sequence signature...
Select this article
Research: Cis-acting variation is common across regulatory layers but is often buffered during embryonic development
- Swann Floc'hlay,
- Emily S. Wong,
- Bingqing Zhao,
- Rebecca R. Viales,
- Morgane Thomas-Chollier,
- Denis Thieffry,
- David A. Garfield,
- and Eileen E.M. Furlong
Genome Res. February 2021 31: 211-224; Published in Advance December 11, 2020, doi:10.1101/gr.266338.120
...), whereas cis and trans are balanced for cistrans classified noncoding features.Previous studies suggest that trans-influenced features generally show nonadditive inheritance (Lemos et al. 2008; Meiklejohn et al. 2014; Wong et al. 2017) and are thus less likely to be directly influenced by natural selection...
OPEN ACCESS ARTICLE
Select this article
Research: The roles of cis- and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression
- Colin D. Meiklejohn,
- Joseph D. Coolon,
- Daniel L. Hartl,
- and Patricia J. Wittkopp
Genome Res. January 2014 24: 84-95; Published in Advance September 16, 2013, doi:10.1101/gr.156414.113
...-acting factors to DNA and their effects on the expression of nearby genes. Studies of the genetic control of gene expression indicate that there is abundant variation within natural populations in both cis- and trans-regulation and that both modes contribute to adaptation and divergence between species (Wray...
OPEN ACCESS ARTICLE
Select this article
Research: Extensive compensatory cis-trans regulation in the evolution of mouse gene expression
- Angela Goncalves,
- Sarah Leigh-Brown,
- David Thybert,
- Klara Stefflova,
- Ernest Turro,
- Paul Flicek,
- Alvis Brazma,
- Duncan T. Odom,
- and John C. Marioni
Genome Res. December 2012 22: 2376-2384; Published in Advance August 23, 2012, doi:10.1101/gr.142281.112
.... We propose that expression levels of genes regulated by this mechanism are fine-tuned by cis variants that arise following regulatory changes in trans , suggesting that many cis variants are not the primary targets of natural selection. Footnotes ↵ 7 Corresponding authors E...
OPEN ACCESS ARTICLE
Select this article
Research: Positive selection in noncoding genomic regions of vocal learning birds is associated with genes implicated in vocal learning and speech functions in humans
- James A. Cahill,
- Joel Armstrong,
- Alden Deran,
- Carolyn J. Khoury,
- Benedict Paten,
- David Haussler,
- and Erich D. Jarvis
Genome Res. November 2021 31: 2035-2049; Published in Advance October 19, 2021, doi:10.1101/gr.275989.121
...gene expression convergence related to vocal learning, speech, and song. To understand the evolutionary basis of vocal learning gene specializations and convergence, we searched for and identified accelerated genomic regions (ARs), a marker of positive selection, specific to vocal learning birds. We...
OPEN ACCESS ARTICLE
Select this article
Research: Coevolution within a transcriptional network by compensatory trans and cis mutations
- Dwight Kuo,
- Katherine Licon,
- Sourav Bandyopadhyay,
- Ryan Chuang,
- Colin Luo,
- Justin Catalana,
- Timothy Ravasi,
- Kai Tan,
- and Trey Ideker
Genome Res. December 2010 20: 1672-1678; Published in Advance October 26, 2010, doi:10.1101/gr.111765.110
...– 1797 . ↵ Emerson JJ , Hsieh LC , Sung HM , Wang TY , Huang CJ , Lu HH , Lu MY , Wu SH , Li WH Emerson JJ , Hsieh LC , Sung HM , Wang TY , Huang CJ , Lu HH , Lu MY , Wu SH , Li WH . 2010 . Natural selection on cis and trans regulation in yeasts . Genome Res 20 : 826 – 836 . ↵ Fernandes L , Rodrigues...
OPEN ACCESS ARTICLE
Select this article
Method: Massively parallel cis-regulatory analysis in the mammalian central nervous system
- Susan Q. Shen,
- Connie A. Myers,
- Andrew E.O. Hughes,
- Leah C. Byrne,
- John G. Flannery,
- and Joseph C. Corbo
Genome Res. February 2016 26: 238-255; Published in Advance November 17, 2015, doi:10.1101/gr.193789.115
...with a selectable range of fragment sizes for targeted cis-regulome analysis. As a built-in feature, our approach Corresponding author: jcorbo@wustl.edu Article published online before print. Article, supplemental material, and publication date are at http://www..org/cgi/doi/10.1101/gr.193789.115. © 2016 Shen et al...
Select this article
Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
- Andrew D. Bates,
- Dawid Grzela,
- Maciej Studzian,
- Louise Brennan,
- Moli Williams,
- Conor Fawcett,
- Beth Hammond,
- Manreen Grewal,
- Marcin Ratajewski,
- Lukasz Pulaski,
- and Urszula L. McClurg
Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
...relevance, integrating the origin of DNA and protein elements (cis and trans) to evaluate false-positive and false-negative risks across experimental systems. Moreover, we explore how perturbation strategies—gain and loss of function—can complement steady-state profiling to establish causality in gene...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Emerson et al. 20 (6): 826.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: