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Elkon et al. 13 (5): 773
.
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290
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:
Genome-wide identification of tandem repeats associated with splicing variation across 49 tissues in humans
Kohei Hamanaka
,
Daisuke Yamauchi
,
Eriko Koshimizu
,
Kei Watase
,
Kaoru Mogushi
,
Kinya Ishikawa
,
Hidehiro Mizusawa
,
Naomi Tsuchida
,
Yuri Uchiyama
,
Atsushi Fujita
,
Kazuharu Misawa
,
Takeshi Mizuguchi
,
Satoko Miyatake
,
and
Naomichi Matsumoto
Genome Res.
March 2023
33
:
435
-
447
;
Published in Advance
March 27, 2023
,
doi:
10.1101/gr.277335.122
...for five repeat motifs (Q-value < 0.1). Then, using SpliceAid and ATtRACT, we predicted which RBPs bind to the motifs (Fig. 3B; Supplemental Table S5; Piva et al. 2009; Giudice et al. 2016). These experimental and in
silico
analyses pointed out the several common RBPs. Next, we sought to identify examples...
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Research
:
Genome-wide redistribution of 24-nt siRNAs in rice gametes
Chenxin Li
,
Hengping Xu
,
Fang-Fang Fu
,
Scott D. Russell
,
Venkatesan Sundaresan
,
and
Jonathan I. Gent
Genome Res.
February 2020
30
:
173
-
184
;
Published in Advance
January 2, 2020
,
doi:
10.1101/gr.253674.119
...cell could be explained by simple loss of 24-nt siRNAs from canonical RdDM loci because 24-nt siRNAs remained abundant relative to other siRNA lengths and even increased in abundance relative to miRNAs. In addition, removal of 24-nt siRNAs from canonical RdDM loci in
silico
and analysis of the residual...
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Method
:
Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling
Mattia Furlan
,
Eugenia Galeota
,
Nunzio Del Gaudio
,
Erik Dassi
,
Michele Caselle
,
Stefano de Pretis
,
and
Mattia Pelizzola
Genome Res.
October 2020
30
:
1492
-
1507
;
Published in Advance
September 25, 2020
,
doi:
10.1101/gr.260984.120
...be in
silico
separated from pre-existing RNA (Herzog et al. 2017; Baptista and Dölken 2018; Jürges et al. 2018; Schofield et al. 2018). A number of methods were developed for the quantification of RNA dynamics via metabolic labeling, including INSPEcT (de Pretis et al. 2015), DRUID (Lugowski et al. 2018), c...
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:
Genome wide analysis of 3′ UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish
Charles E. Vejnar
,
Mario Abdel Messih
,
Carter M. Takacs
,
Valeria Yartseva
,
Panos Oikonomou
,
Romain Christiano
,
Marlon Stoeckius
,
Stephanie Lau
,
Miler T. Lee
,
Jean-Denis Beaudoin
,
Damir Musaev
,
Hiba Darwich-Codore
,
Tobias C. Walther
,
Saeed Tavazoie
,
Daniel Cifuentes
,
and
Antonio J. Giraldez
Genome Res.
July 2019
29
:
1100
-
1114
;
Published in Advance
June 21, 2019
,
doi:
10.1101/gr.245159.118
...-coding
transcripts
. The UTRs and CDS of each
transcript
were split into 50 bins to normalize their length. Metaplots averaged over each RBP were clustered to group similar binding profiles. (G) Heatmap representing in
silico
binding profiles obtained by scanning for RBP binding motifs within protein...
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Method
:
Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI
Ruben Boers
,
Joachim Boers
,
Bas de Hoon
,
Christel Kockx
,
Zeliha Ozgur
,
Anco Molijn
,
Wilfred van IJcken
,
Joop Laven
,
and
Joost Gribnau
Genome Res.
January 2018
28
:
88
-
99
;
Published in Advance
December 8, 2017
,
doi:
10.1101/gr.222885.117
...encompasses restriction enzyme digestion and adaptor ligation, size selection, PCR amplification, and sequencing (Fig. 1A), followed by in
silico
analysis involving a CG filter, to retrieve the correct fragments and reduce noise, subsequent alignment, and DMR calling (Fig. 1B).View larger version...
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:
Genome-wide discovery of human splicing branchpoints
Tim R. Mercer
,
Michael B. Clark
,
Stacey B. Andersen
,
Marion E. Brunck
,
Wilfried Haerty
,
Joanna Crawford
,
Ryan J. Taft
,
Lars K. Nielsen
,
Marcel E. Dinger
,
and
John S. Mattick
Genome Res.
February 2015
25
:
290
-
303
;
Published in Advance
January 5, 2015
,
doi:
10.1101/gr.182899.114
...
Genome-wide
discovery of human splicing branchpoints Tim R. Mercer 1 , 2 , 8 , Michael B. Clark 1 , 3 , 8 , Stacey B. Andersen 4 , Marion E. Brunck 4 , Wilfried Haerty 3 , Joanna Crawford 5 , Ryan J...
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Method
:
Accurate typing of short tandem repeats from genome-wide sequencing data and its applications
Arkarachai Fungtammasan
,
Guruprasad Ananda
,
Suzanne E. Hile
,
Marcia Shu-Wei Su
,
Chen Sun
,
Robert Harris
,
Paul Medvedev
,
Kristin Eckert
,
and
Kateryna D. Makova
Genome Res.
May 2015
25
:
736
-
749
;
Published in Advance
March 30, 2015
,
doi:
10.1101/gr.185892.114
...Accurate typing of short tandem repeats from
genome-wide
sequencing data and its applications Arkarachai Fungtammasan 1 , 2 , 3 , 4 , 8 , Guruprasad Ananda 1 , 3 , 4 , 5 , 8 , 9 , Suzanne E. Hile 3 , 6 , Marcia Shu-Wei Su 2 , 3...
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:
Genome-wide identification of long noncoding natural antisense transcripts and their responses to light in
Arabidopsis
Huan Wang
,
Pil Joong Chung
,
Jun Liu
,
In-Cheol Jang
,
Michelle J. Kean
,
Jun Xu
,
and
Nam-Hai Chua
Genome Res.
March 2014
24
:
444
-
453
;
Published in Advance
January 8, 2014
,
doi:
10.1101/gr.165555.113
...
Genome-wide
identification
of long noncoding natural antisense
transcripts
and their responses to light in Arabidopsis Huan Wang 1 , 4 , Pil Joong Chung 1 , 2 , 4 , Jun Liu 1 , In-Cheol Jang 1 , 3 , Michelle J. Kean 1 , Jun Xu...
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:
Modeling transcriptional regulation of model species with deep learning
Evan M. Cofer
,
João Raimundo
,
Alicja Tadych
,
Yuji Yamazaki
,
Aaron K. Wong
,
Chandra L. Theesfeld
,
Michael S. Levine
,
and
Olga G. Troyanskaya
Genome Res.
June 2021
31
:
1097
-
1105
;
Published in Advance
April 22, 2021
,
doi:
10.1101/gr.266171.120
...Ark,” modeling the cis-regulatory activities of four of the most widely studied model organisms: C. elegans, D. rerio, D. melanogaster, and M. musculus (Fig. 1A). To the best of our knowledge, DeepArk is the first such resource for these model organisms. DeepArk provides an in
silico
ChIP-seq capability: Given...
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Research
:
Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus
Rhizophagus irregularis
Alexandra Dallaire
,
Bethan F. Manley
,
Maya Wilkens
,
Iliana Bista
,
Clement Quan
,
Edouard Evangelisti
,
Charles R. Bradshaw
,
Navin B. Ramakrishna
,
Sebastian Schornack
,
Falk Butter
,
Uta Paszkowski
,
and
Eric A. Miska
Genome Res.
December 2021
31
:
2290
-
2302
;
Published in Advance
November 12, 2021
,
doi:
10.1101/gr.275752.121
...that a well-
controlled
TE activity directly contributes to evolution in AM fungi.The arbuscular mycorrhizal (AM) symbiosis is hundreds of millions of years old and a majority of the world's plant species are hosts to AM fungi (AMF) (Lutzoni et al. 2018). As such, these fungi exist in a wide range...
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