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  1. ...RNA inferred MD-score and the transcription level (FPKM) of the gene encoding the TF (Supplemental Fig. S14B), suggesting that some TFs are themselves regulated at transcription. However, the observed correlations were often weak and complex—typically neither linear or monotonic—consistent with the observation...
  2. ..., J. and Ehrenberg, M. 2003 . Fast evaluation of fluctuations in biochemical networks with the linear noise approximation. Genome Res. (this issue). ↵ Elf, J., Nilsson, D., Tenson, T., and Ehrenberg, M. 2003 . Selective charging of tRNA isoacceptors explains patterns of codon usage. Science 300 : 1718...
  3. ...maturation. Genome Res. 13 : (this issue). Elf, J., and Ehrenberg, M. 2003 . Fast evaluation of fluctuations in biochemical networks with the linear noise approximation. Genome Res. 13 : (this issue). Jensen, L.J., Ussery, D.W., and Brunak, S. 2003 . Functionality of system components: Conservation...
  4. ...of smooth underlying growth functions through the length-scale parameter, explicitly accounting for experimental noise. This is in contrast to other recent models such as linear spline fitting in generalized additive models (GAMs), which are sensitive to technical variation (Sekse et al. 2012...
  5. ...line) alignments; (black dotted line) perfectly separates correct from incorrect alignments. (Inset) The receiver operating characteristic (ROC) curve for the linear SVM classifier separating orthologous from control alignments; the curve profiles the performance in terms of the number of orthologous...
  6. ...) ( Fig. 3A ) correlated most strongly with the ability to predict its dynamics based upon the changes in the measured oxygen tension levels via a linear model (Supplemental Fig. 2) ( Bonneau et al. 2006 ). We therefore used the values along the PC1 axis to assign the “oxic score” to each cluster, which...
  7. ...are between −0.262 and 0.262 (0.833 and 1.199 when expressed as linear ratios) for the unamplified experiment. The same confidence bounds calculated for the unamplified experiment are replicated in the plot of ratios generated by microarray analysis of amplified DNA. Evaluation of DNA Amplification Bias Using...
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