Searching journal content for articles similar to Ekdahl et al. 22 (8): 1477.

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  1. Research: RNA Pol II–dependent transcription efficiency fine-tunes A-to-I editing levels
    • Brigitta Szabo,
    • Therese C. Mandl,
    • Bernhard Woldrich,
    • Gregor Diensthuber,
    • David Martin,
    • Michael F. Jantsch,
    • and Konstantin Licht
    Genome Res. February 2024 34: 231-242; Published in Advance March 12, 2024, doi:10.1101/gr.277686.123
    ...RNA Pol II–dependent transcription efficiency fine-tunes A-to-I editing levels Brigitta Szabo, Therese C. Mandl, Bernhard Woldrich, Gregor Diensthuber, David Martin, Michael F. Jantsch and Konstantin Licht Department of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical...
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  2. Research: A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations
    • Te-Lun Mai and
    • Trees-Juen Chuang
    Genome Res. November 2019 29: 1766-1776; Published in Advance September 12, 2019, doi:10.1101/gr.246033.118
    ...Te-Lun Mai and Trees-Juen Chuang Genomics Research Center, Academia Sinica, Taipei 11529, Taiwan Corresponding author: trees@gate.sinica.edu.twAbstractAdenosine-to-inosine (A-to-I) RNA editing is a very common co-/posttranscriptional modification that can lead to A-to-G changes at the RNA level...
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  3. Research: Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
    • Yumeng Wang,
    • Xiaoyan Xu,
    • Shuangxing Yu,
    • Kang Jin Jeong,
    • Zhicheng Zhou,
    • Leng Han,
    • Yiu Huen Tsang,
    • Jun Li,
    • Hu Chen,
    • Lingegowda S. Mangala,
    • Yuan Yuan,
    • A. Karina Eterovic,
    • Yiling Lu,
    • Anil K. Sood,
    • Kenneth L. Scott,
    • Gordon B. Mills,
    • and Han Liang
    Genome Res. July 2017 27: 1112-1125; Published in Advance April 14, 2017, doi:10.1101/gr.219741.116
    ...that at least 300–400 highly expressed miRNAs are evolutionarily conserved and play important biological roles (Liang and Li 2009; Chiang A-to-I microRNA editing hotspots in cancer Genome Research 1113 www..org et al. 2010). Thus, these editedmiRNAs have the potential to functionally regulate target genes...
  4. Resource: A biochemical landscape of A-to-I RNA editing in the human brain transcriptome
    • Masayuki Sakurai,
    • Hiroki Ueda,
    • Takanori Yano,
    • Shunpei Okada,
    • Hideki Terajima,
    • Toutai Mitsuyama,
    • Atsushi Toyoda,
    • Asao Fujiyama,
    • Hitomi Kawabata,
    • and Tsutomu Suzuki
    Genome Res. March 2014 24: 522-534; Published in Advance January 9, 2014, doi:10.1101/gr.162537.113
    ...A biochemical landscape of A-to-I RNA editing in the human brain transcriptome Masayuki Sakurai 1 , 4 , Hiroki Ueda 1 , 4 , Takanori Yano 1 , Shunpei Okada 1 , Hideki Terajima 1 , Toutai Mitsuyama 2 , Atsushi Toyoda 3...
  5. Method: Accurate identification of A-to-I RNA editing in human by transcriptome sequencing
    • Jae Hoon Bahn,
    • Jae-Hyung Lee,
    • Gang Li,
    • Christopher Greer,
    • Guangdun Peng,
    • and Xinshu Xiao
    Genome Res. January 2012 22: 142-150; Published in Advance September 29, 2011, doi:10.1101/gr.124107.111
    ...Accurate identification of A-to-I RNA editing in human by transcriptome sequencing Jae Hoon Bahn 1 , Jae-Hyung Lee 1 , Gang Li , Christopher Greer , Guangdun Peng and Xinshu Xiao 2 Department of Integrative Biology...
  6. Research: A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes
    • Lily Bazak,
    • Ami Haviv,
    • Michal Barak,
    • Jasmine Jacob-Hirsch,
    • Patricia Deng,
    • Rui Zhang,
    • Farren J. Isaacs,
    • Gideon Rechavi,
    • Jin Billy Li,
    • Eli Eisenberg,
    • and Erez Y. Levanon
    Genome Res. March 2014 24: 365-376; Published in Advance December 17, 2013, doi:10.1101/gr.164749.113
    ...accounts for only 0.013% of A-to-I deamination reactions in the primate brain cell, and all recoding sites examined, combined, explain no more than 0.073% of all A-to-I editing activity in this tissue. Looking at other tissues we found editing in all 22 recoding sites to range between <0.001%and 0...
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  7. Research: Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development
    • Suba Rajendren,
    • Alfa Dhakal,
    • Pranathi Vadlamani,
    • Jack Townsend,
    • Sarah N. Deffit,
    • and Heather A. Hundley
    Genome Res. January 2021 31: 27-39; Published in Advance December 18, 2020, doi:10.1101/gr.267575.120
    ...Corresponding author: hahundle@indiana.eduAbstractAdenosine (A) to inosine (I) RNA editing contributes to transcript diversity and modulates gene expression in a dynamic, cell type–specific manner. During mammalian brain development, editing of specific adenosines increases, whereas the expression of A-to-I...
  8. Method: Systematic identification of edited microRNAs in the human brain
    • Shahar Alon,
    • Eyal Mor,
    • Francois Vigneault,
    • George M. Church,
    • Franco Locatelli,
    • Federica Galeano,
    • Angela Gallo,
    • Noam Shomron,
    • and Eli Eisenberg
    Genome Res. August 2012 22: 1533-1540; Published in Advance April 12, 2012, doi:10.1101/gr.131573.111
    ...RNAs are formed as part of the microRNA (miRNA) maturation process, and it is therefore expected that miRNAs are affected by A-to-I editing. Editing of miRNAs has the potential to add another layer of complexity to gene regulation pathways, especially if editing occurs within the miRNA–mRNA recognition site. Thus...
  9. Resource: The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting
    • Lishi Li,
    • Yulong Song,
    • Xinrui Shi,
    • Jianheng Liu,
    • Shaolei Xiong,
    • Wanying Chen,
    • Qiang Fu,
    • Zichao Huang,
    • Nannan Gu,
    • and Rui Zhang
    Genome Res. January 2018 28: 132-143; Published in Advance December 12, 2017, doi:10.1101/gr.224386.117
    ..., Guangzhou 510275, PR China ↵2 Co-first authors, listed alphabetically Corresponding authors: zhangrui3@mail.sysu.edu.cn, gnannan3@mail.sysu.edu.cnAbstractAdenosine-to-inosine (A-to-I) RNA editing regulates miRNA biogenesis and function. To date, fewer than 160 miRNA editing sites have been identified. Here...
  10. Methods: Cross-mapping and the identification of editing sites in mature microRNAs in high-throughput sequencing libraries
    • Michiel J.L. de Hoon,
    • Ryan J. Taft,
    • Takehiro Hashimoto,
    • Mutsumi Kanamori-Katayama,
    • Hideya Kawaji,
    • Mitsuoki Kawano,
    • Mami Kishima,
    • Timo Lassmann,
    • Geoffrey J. Faulkner,
    • John S. Mattick,
    • Carsten O. Daub,
    • Piero Carninci,
    • Jun Kawai,
    • Harukazu Suzuki,
    • and Yoshihide Hayashizaki
    Genome Res. February 2010 20: 257-264; Published in Advance January 5, 2010, doi:10.1101/gr.095273.109
    ..., although there are also examples ofmiRNAs interacting with 59 UTRs and promoter regions (Lee et al. 2009). Several recent studies have reported evidence of adenosine to inosine (A-to-I) editing in pri-miRNAs (Luciano et al. 2004; Blow et al. 2006; Kawahara et al. 2008). Such editing can affect the efficacy...
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