Searching journal content for articles similar to Do Kim et al. 16 (7): 901.

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  1. ...in mice housing the α-globin gene cluster, delineate the chromatin region where enhancers gain access and interact with responsive promoters, which underscored the association of hierarchical TADs with gene-specific regulation. Moreover, several studies have documented a category of partially overlapping...
  2. ...(downstream) genes are colored green. (C) Relative gene expression of Nes and Bcan across ES 2i, ES serum, and NPC cellular states. (D) Interaction cluster outlines of the loop boxed in magenta in B. Plot is overlaid with ChIP-seq tracks of H3K27ac, YY1, and CTCF in the ES 2i, ES serum, and NPC conditions...
  3. ...modifications that distinguish thematernal and paternal s at these loci (Reik and Walter 2001; Dindot et al. 2009). More than 60 imprinted genes have been identified in humans (http://www.geneimprint.com/), and their clustered nature suggests that many are regulated by regional control mechanisms. To date...
  4. ....J. ( 2005 ) Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF . Mol. Cell 20 : 483 – 489 . ↵ Donohoe, M.E. , Zhang, L.F. , Xu, N. , Shi, Y. , Lee, J.T. ( 2007 ) Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch . Mol. Cell 25 : 43 – 56...
  5. ...isolated repetitive regions of the and identified those containing at least one YY1 motif for phylogenetic analysis. This phylogenetic analysis revealed that most of these unannotated repetitive regions from autosomal sequences do not cluster by chromosome. In contrast, sequences derived from the X...
  6. ...transcription factor occupancy. (A) For each transcription factor, the position weight matrix (PWM) of its known motif and its DNA-binding domain (DBD) type are shown. (B) Pairwise comparisons of normalized GABPA, MAX, NRF1, SP1, or YY1 ChIP-seq signal for all identified occupancy peaks. Regions...
  7. ...identified and best characterized to date human lncRNA. Recently, lncRNAs have been implicated in imprinting and long-range gene regulation with functional properties of enhancers (Khalil et al. 2009; Mattick 2010;Wang and Chang 2011). Here, we demonstrate that loss of a distant enhancer region in a protein...
  8. ...is partially recognizable in fish. Identification of paralogous genes in the human Besides the BWS orthologous genes in Fugu and zebrafish we identified a number of paralogs in other chromosomal regions (Supplemental Tables 1, 2). In addition, paralogs have previously been described for a few imprinted BWS...
  9. ...by TFs. Ultimately, targeting intergenic regions shown to have functional consequence may improve future microarray- and sequencing-based association studies by increasing coverage with only a modest effect on statistical power. Results Transcription factors often cluster together on the same alleles...
  10. ...)—map within an intron of Ev1 and between Yy1 and Wars genes, respectively. Imprinting status of mir-342 remains unsolved as we failed to detect it in embryos. An intergenic germ-line derived differentially methylated region (IG-DMR) located between Dlk1 and Gtl2 genes is represented by circles (filled...
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