Searching journal content for articles similar to Daza-Vamenta et al. 14 (8): 1501.

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  1. ...characterize these complex regions to gain insight into the impact of genomic diversity on health and disease. Here we resolve the organization of complete major histocompatibility complex (MHC) class II regions in rhesus macaques by using a long-read sequencing strategy (Oxford Nanopore Technologies...
  2. ...of human diseases. Although the macaque major histocompatibility complex (MHC) region shares most features with the human leukocyte antigen (HLA) region, macaques have an expanded repertoire of MHC class I genes. Although a chimera of two rhesus macaque MHC haplotypes was first published in 2004...
  3. .... Unraveling the architecture of major histocompatibility complex class II haplotypes in rhesus macaques. Genome Res (this issue) 34: 1811–1824. doi:10.1101/gr.278968.124 ↵Diensthuber G, Pryszcz LP, Llovera L, Lucas MC, Delgado-Tejedor A, Cruciani S, Roignant J-Y, Begik O, Novoa EM. 2024. Enhanced detection...
  4. ...14, CN-T2T, IPD-IMGT/HLA, and IPD-IMGT/MHC, including 198 HLA-DRB1, seven HLA-DRB3, four HLA-DRB4, and six HLA-DRB5 unique CDSs in total. DRB CDSs from non-human primate species, chimpanzee (patr), crab-eating macaque (mafa), and rhesus monkey (mamu), are used as the outgroup for tree construction...
  5. ...variations of a pedigreed C. a. sabaeus population. Through comparative analyses with human and rhesus macaque, we characterize at high resolution the unique chromosomal fission events that differentiate the vervets and their close relatives from most other catarrhine primates, in whom karyotype is highly...
  6. ...may open the opportunity for HLA and KIR genotyping across various sequencing applications. Introduction Polymorphisms in immune receptor genes diversify the immune response, which strengthens the resilience of a population to diseases. In particular, major histocompatibility complex (MHC) encoded...
  7. ...selected genes (PSGs) in which there is statistically significant evidence of an acceleration in the rate of amino acid changes on the human or chimpanzee lineages since the two species diverged (Bakewell et al. 2007; Rhesus Macaque Genome Sequencing and Analysis Consortium 2007). Intriguingly...
  8. ...). These two species diverged from humans ∼5 and ∼30 Mya, respectively ( Horai 1995 ; Kumar and Hedges 1998 ). A family of KIR cDNA has been characterized in common chimpanzee ( Khakoo et al. 2000 ) and rhesus macaque ( Grendell et al. 2001 ; Hershberger et al. 2001 ) as well as bonobo ( Rajalingam et al. 2001...
  9. ...is as follows: human 84/0, Pan lineage 75/4, gorilla 88/14, orangutan 107/10, gibbon 336/213, OWM (baboon and macaque combined) 211/158, marmoset 408/135, and lemur 1209/3530.The evolutionary age of each lineage in millions of years (depicted by the horizontal line) refers to the approximate divergence times...
  10. ...or more individuals and a relatively high error rate for individual reads. Applying this method to data from the Celera human sequencing and SNP discovery project, we obtain estimates of nucleotide diversity in windows spanning the human and show that the diversity to divergence ratio is reduced...
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