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  1. ...of these was disrupted in at least one of the 14,115 Streptococcus s in RefSeq. This is a common problem for core analyses, especially because the multiple contigs within draft s can result in the absence of multiple genes from assemblies. Core schemes used for cgMLST are therefore usually based on a relaxed core...
  2. ..., Vibrio, and Moraxella and genotyped those assemblies by core multilocus sequence typing (cgMLST). Hierarchical clustering of cgMLST sequence types allows mapping a new bacterial strain to predefined population structures at multiple levels of resolution within a few hours after uploading its short reads...
  3. ...). Both species reproduce as hermaphrodites, which made them important model organisms with the associated establishment of extensive technology platforms as indicated above. P. pacificus and C. elegans are thought to have shared a last common ancestor ∼100 mya (Prabh et al. 2018; Werner et al. 2018...
  4. ...to the last common ancestor (LCA) of life. We used the Clusters of Orthologous Groups of proteins (COG) database ( Tatusov et al. 2001 ) to search for constituents of the genetic core by identifying the universally conserved set of related genes that have the same phylogenetic history as rRNA. If a gene...
  5. .... 184 : 2072 -2080. ↵ Daubin, V., Gouy, M., and Perrière, G. 2002 . A phylogenomic approach to bacterial phylogeny: Evidence of a core of genes sharing a common history. Genome Res. 12 : 1080 -1090. ↵ Daubin, V., Moran, N.A., and Ochman, H. 2003 . Phylogenetics and the cohesion of bacterial s. Science...
  6. ...University, Ithaca, New York 14853, USA Abstract An open question in bacterial genomics is the role that adaptive evolution of the core genome plays in diversification and adaptation of bacterial species, and how this might differ between groups of bacteria occupying different environmental...
  7. ...in the organization, stability, regulation, and evolution of s (Bourque et al. 2018; Wells and Feschotte 2020). At broad scale, REs shape chromatin domains across chromosomes and impact the three-dimensional organization of DNA (Winter et al. 2018; Sun et al. 2020). Rapidly evolving blocks of REs are common sites...
  8. ...).Although Blastocystis is widespread across vertebrates, there is limited evidence for co-phylogeny of Blastocystis subtypes with their host (Fig. 1). Instead, the Blastocystis phylogeny more closely resembles that of spore-forming gut bacteria (Moeller et al. 2016), with host switching as a common...
  9. ...lineage-specific activity. Together with the presence of representative elements in several other Pezizales species, this makes Tuberaceae an iconic example of how an apparently common size expansion within a clade can be driven by parallel genomic trajectories, involving the differential lineage...
  10. ...(default), dividing queries into bins of novelty (d*). (C,D) Evaluation of simple ranking strategies (discriminative, common, random) implemented using species counts R or children counts, R′ and our new weighted-sum, R* heuristic [Equation (11)]. See Supplemental Figure S2 for an illustration of functions...
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