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Cutter and Choi 20 (8): 1103
.
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16
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Research
:
Natural variation in
C. elegans
short tandem repeats
Gaotian Zhang
,
Ye Wang
,
and
Erik C. Andersen
Genome Res.
October 2022
32
:
1852
-
1861
;
Published in Advance
October 4, 2022
,
doi:
10.1101/gr.277067.122
...been identified among wild
Caenorhabditis
elegans strains, the
natural
diversity in STRs remains unknown. Here, we characterized the distribution of 31,991 STRs with motif lengths of 1–6 bp in the reference of C. elegans. Of these STRs, 27,667 harbored
polymorphisms
across
540 wild strains and only...
Abstract
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Research
:
Full-genome evolutionary histories of selfing, splitting, and selection in
Caenorhabditis
Cristel G. Thomas
,
Wei Wang
,
Richard Jovelin
,
Rajarshi Ghosh
,
Tatiana Lomasko
,
Quang Trinh
,
Leonid Kruglyak
,
Lincoln D. Stein
,
and
Asher D. Cutter
Genome Res.
May 2015
25
:
667
-
678
;
Published in Advance
March 17, 2015
,
doi:
10.1101/gr.187237.114
...- sequencing of 37 wild isolates of the
nematode
C.
briggsae
and applied a pairwise sequentially Markovian coalescent (PSMC) model to 703 combinations of
genomic
haplotypes to draw inferences about population history, the
genomic
scope of
natural
selection
, and to compare with 40 wild isolates of C. elegans...
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Research
:
Pangenome analysis reveals families of ubiquitin-ligase adaptors as key genomic divergence drivers that lead to hybrid incompatibility
Dongying Xie
,
Pohao Ye
,
Yiming Ma
,
and
Zhongying Zhao
Genome Res.
March 2026
36
:
506
-
521
;
Published in Advance
February 17, 2026
,
doi:
10.1101/gr.280885.125
...be overlooked in traditional pairwise comparative analyses relying on a single reference per population or species.The
nematode
species pair
Caenorhabditis
briggsae
and
Caenorhabditis
nigoni has emerged as a powerful model for dissecting the genetic and
genomic
bases of speciation. Although both species...
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Research
:
Mutability of mononucleotide repeats, not oxidative stress, explains the discrepancy between laboratory-accumulated mutations and the natural allele-frequency spectrum in
C. elegans
Moein Rajaei
,
Ayush Shekhar Saxena
,
Lindsay M. Johnson
,
Michael C. Snyder
,
Timothy A. Crombie
,
Robyn E. Tanny
,
Erik C. Andersen
,
Joanna Joyner-Matos
,
and
Charles F. Baer
Genome Res.
September 2021
31
:
1602
-
1613
;
Published in Advance
August 17, 2021
,
doi:
10.1101/gr.275372.121
...
selection
biases the standing genetic variation.The
nematode
Caenorhabditis
elegans is an important model organism in many areas of biology and was the first metazoan organism to have its mutational process characterized at the
genomic
level (Denver et al. 2000, 2004b). As
genomic
sequence data from C...
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Resource
:
The million mutation project: A new approach to genetics in
Caenorhabditis elegans
Owen Thompson
,
Mark Edgley
,
Pnina Strasbourger
,
Stephane Flibotte
,
Brent Ewing
,
Ryan Adair
,
Vinci Au
,
Iasha Chaudhry
,
Lisa Fernando
,
Harald Hutter
,
Armelle Kieffer
,
Joanne Lau
,
Norris Lee
,
Angela Miller
,
Greta Raymant
,
Bin Shen
,
Jay Shendure
,
Jon Taylor
,
Emily H. Turner
,
LaDeana W. Hillier
,
Donald G. Moerman
,
and
Robert H. Waterston
Genome Res.
October 2013
23
:
1749
-
1762
;
Published in Advance
June 25, 2013
,
doi:
10.1101/gr.157651.113
..., Robert H Armelle Hutter, H Vinci Au Donald Strasbourger Pnina Angela Miller Pnina Chaudhry 10.1101/gr.157651.113 1088-9051
genome
;gr.157651.113 The million mutation project: A new approach to genetics in
Caenorhabditis
elegans Resource The million mutation project: A new approach to genetics...
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Research
:
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth
Christina A. Cuomo
,
Christopher A. Desjardins
,
Malina A. Bakowski
,
Jonathan Goldberg
,
Amy T. Ma
,
James J. Becnel
,
Elizabeth S. Didier
,
Lin Fan
,
David I. Heiman
,
Joshua Z. Levin
,
Sarah Young
,
Qiandong Zeng
,
and
Emily R. Troemel
Genome Res.
December 2012
22
:
2478
-
2488
;
Published in Advance
July 18, 2012
,
doi:
10.1101/gr.142802.112
...address questions about microsporidia biology and evolution. We sequenced three microsporidian
genomes
from two species, Nematocida parisii and Nematocida sp1, which are
natural
pathogens of
Caenorhabditis
nematodes
and provide model systems for studying microsporidian pathogenesis. We performed...
Abstract
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Research
:
An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement
Ignacio Maeso
,
Manuel Irimia
,
Juan J. Tena
,
Esther González-Pérez
,
David Tran
,
Vydianathan Ravi
,
Byrappa Venkatesh
,
Sonsoles Campuzano
,
José Luis Gómez-Skarmeta
,
and
Jordi Garcia-Fernàndez
Genome Res.
April 2012
22
:
642
-
655
;
Published in Advance
January 10, 2012
,
doi:
10.1101/gr.132233.111
...An ancient
genomic
regulatory block conserved
across
bilaterians and its dismantling in tetrapods by retrogene replacement Ignacio Maeso 1 , 6 , 8 , 9 , Manuel Irimia 1 , 7 , 8 , 9 , Juan J. Tena 2 , 8 , Esther González-Pérez 3 , 8...
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LETTER
:
The amphioxus genome illuminates vertebrate origins and cephalochordate biology
Linda Z. Holland
,
Ricard Albalat
,
Kaoru Azumi
,
Èlia Benito-Gutiérrez
,
Matthew J. Blow
,
Marianne Bronner-Fraser
,
Frederic Brunet
,
Thomas Butts
,
Simona Candiani
,
Larry J. Dishaw
,
David E.K. Ferrier
,
Jordi Garcia-Fernàndez
,
Jeremy J. Gibson-Brown
,
Carmela Gissi
,
Adam Godzik
,
Finn Hallböök
,
Dan Hirose
,
Kazuyoshi Hosomichi
,
Tetsuro Ikuta
,
Hidetoshi Inoko
,
Masanori Kasahara
,
Jun Kasamatsu
,
Takeshi Kawashima
,
Ayuko Kimura
,
Masaaki Kobayashi
,
Zbynek Kozmik
,
Kaoru Kubokawa
,
Vincent Laudet
,
Gary W. Litman
,
Alice C. McHardy
,
Daniel Meulemans
,
Masaru Nonaka
,
Robert P. Olinski
,
Zeev Pancer
,
Len A. Pennacchio
,
Mario Pestarino
,
Jonathan P. Rast
,
Isidore Rigoutsos
,
Marc Robinson-Rechavi
,
Graeme Roch
,
Hidetoshi Saiga
,
Yasunori Sasakura
,
Masanobu Satake
,
Yutaka Satou
,
Michael Schubert
,
Nancy Sherwood
,
Takashi Shiina
,
Naohito Takatori
,
Javier Tello
,
Pavel Vopalensky
,
Shuichi Wada
,
Anlong Xu
,
Yuzhen Ye
,
Keita Yoshida
,
Fumiko Yoshizaki
,
Jr-Kai Yu
,
Qing Zhang
,
Christian M. Zmasek
,
Pieter J. de Jong
,
Kazutoyo Osoegawa
,
Nicholas H. Putnam
,
Daniel S. Rokhsar
,
Noriyuki Satoh
,
and
Peter W.H. Holland
Genome Res.
July 2008
18
:
1100
-
1111
;
Published in Advance
June 18, 2008
,
doi:
10.1101/gr.073676.107
..., including those of protostomes, such as
nematodes
( C. elegans Sequencing Consortium 1998 ; Stein et al. 2003 ) and insects ( Adams et al. 2000 ; Mongin et al. 2004 ; The Honeybee
Genome
Sequencing Consortium 2006 ), and deuterostomes, such as the urochordate Ciona intestinalis ( Dehal et al. 2002...
Abstract
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Letter
:
Comparison of diverse developmental transcriptomes reveals that coexpression of gene neighbors is not evolutionarily conserved
Itai Yanai
and
Craig P. Hunter
Genome Res.
December 2009
19
:
2214
-
2220
;
Published in Advance
September 10, 2009
,
doi:
10.1101/gr.093815.109
...or transcriptional read-through, which may be free of
selective
biases. Here, we compare temporal expression profiles of one-to-one orthologs in conserved or divergent
genomic
positions in two genetically distant
nematode
species—
Caenorhabditis
elegans and C.
briggsae
—that share a near-identical developmental...
Abstract
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ARTICLE
:
The Functional Genomic Distribution of Protein Divergence in Two Animal Phyla: Coevolution, Genomic Conflict, and Constraint
Cristian I. Castillo-Davis
,
Fyodor A. Kondrashov
,
Daniel L. Hartl
,
and
Rob J. Kulathinal
Genome Res.
May 2004
14
:
802
-
811
;
doi:
10.1101/gr.2195604
...annotations, we find a functional
genomic
signature of rapid evolution and
selective
constraint shared between mammalian and
nematode
lineages despite their extensive morphological and ecological differences and distant common ancestry. In both phyla, we find evidence of accelerated evolution among components...
Abstract
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Single-cell gene signature scoring
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Short tandem repeat genotyping using long reads
Spectral component approach for recent population structure
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