Searching journal content for articles similar to Cutler et al. 17 (12): 000.

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  1. ...Variation in histone configurations correlates with gene expression1 across nine inbred strains of mice2 Anna L. Tyler1,∗, Catrina Spruce1,∗, Romy Kursawe2, Annat Haber2, Robyn L. Ball1, Wendy4 A. Pitman1, Alexander D. Fine1, Narayanan Raghupathy1, Michael Walker1, Vivek M. Philip1,5 Christopher L...
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  2. ...compared with SNPs, SVs account for a substantial fraction of characterized molecular genetic variation with phenotypic consequences (Freeman et al. 2006). To examine the likely impact of the identified SVs on gene function, we evaluated the predicted functional effects of the variants in our SV and SNP...
  3. ..., there have been a limited number of pan studies of TE variation within species owing to challenges in assembling and annotating genomic regions containing these highly repetitive elements (Ou et al. 2019). Instead, the vast majority of studies characterizing TE content have used resequencing data mapped...
  4. .... 2023) and found copy-number variation of cis-regulatory elements underlying differences in eud-1 expression and mouth form. However, outside of this case study, it is unknown which nodes of the network are being acted on by evolution. To expand upon these findings, we compared gene expression between...
  5. ...of strain backgrounds for disease modeling to further unlock extant mouse diversity for genetic and genomic studies in health and disease.Hundreds of inbred mouse strains (NCBI:txid10090) and thousands of intercross progeny have been characterized for disease-related traits, developmental characteristics...
  6. ....delledonne@univr.it, r.papa@staff.univpm.itAbstractHigh-throughput genotyping enables the large-scale analysis of genetic diversity in population genomics and -wide association studies that combine the genotypic and phenotypic characterization of large collections of accessions. Sequencing-based approaches...
  7. ...new regulatory elements in support of the Britten–Davidson hypothesis. We characterized inter-specific polymorphisms, structural variants, and polymorphic transposable element insertions and assessed their association to interspecies hybridization-induced gene expression dysregulation related...
  8. ..., populations, and species, and the variation can be attributed to both genetic factors (e.g., rate and landscape modifier loci, architecture, and chromatin structure) and environmental factors (e.g., age, temperature, and pathogen infection) (Stapley et al. 2017). Genome-wide estimates of recombination rate...
  9. ...in chromatin accessibility between species, 30.4% were within lineage-specific SVs and 9.4% were characterized as TE insertions. These TE insertions were localized closer to gene transcription start sites than expected at random and were enriched for sites with significant resemblance to several transcription...
  10. ...invasion with template switching in mouse. Our methodology provides a high-throughput approach for characterization of gene function in meiotic recombination at low animal cost.Homologous recombination (HR) in meiosis is an essential process underlying the production of gametes in sexually reproducing...
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