Searching journal content for articles similar to Clément et al. 12 (2): 281.

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  1. Resource: A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines
    • David B. West,
    • Ravi K. Pasumarthi,
    • Brian Baridon,
    • Esi Djan,
    • Amanda Trainor,
    • Stephen M. Griffey,
    • Eric K. Engelhard,
    • Jared Rapp,
    • Bowen Li,
    • Pieter J. de Jong,
    • and K.C. Kent Lloyd
    Genome Res. April 2015 25: 598-607; Published in Advance January 15, 2015, doi:10.1101/gr.184184.114
    ...of theCcl9 reporter in the dome of Peyer’s patches. A role for CCL9 in GI function has not been described previously. Discussion Although reporter genes have been used in vivo for decades, there are no other published reports of a large survey comparing two different staining strategies, characterizing...
  2. Methods: Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression
    • Mathieu Blanchette,
    • Alain R. Bataille,
    • Xiaoyu Chen,
    • Christian Poitras,
    • Josée Laganière,
    • Céline Lefèbvre,
    • Geneviève Deblois,
    • Vincent Giguère,
    • Vincent Ferretti,
    • Dominique Bergeron,
    • Benoit Coulombe,
    • and François Robert
    Genome Res. May 2006 16: 656-668; Published in Advance April 10, 2006, doi:10.1101/gr.4866006
    ...to be bound in vivo by TFs using ChIP-chip. Their analysis reveals, among other things, that CRM density varies widely across the , with CRM-rich regions often being located near genes encoding transcription factors involved in development. Predicted CRMs show a surprising enrichment near the 3′ end of genes...
  3. METHODS: Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs
    • Manabu Nakayama,
    • Reiko Kikuno,
    • and Osamu Ohara
    Genome Res. November 1, 2002 12: 1773-1784; Published in Advance October 15, 2002, doi:10.1101/gr.406902
    ...Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs Manabu Nakayama 1 , 3 , Reiko Kikuno 1 , and Osamu Ohara 1 , 2 1Department of Human Gene Research, Kazusa...
  4. Research: Vertebrates show coordinated elevated expression of mitochondrial and nuclear genes after birth
    • Hadar Medini and
    • Dan Mishmar
    Genome Res. March 2025 35: 459-474; Published in Advance March 4, 2025, doi:10.1101/gr.279700.124
    ...regulation of mitochondrial–nuclear gene expression (CMNGE) to changing physiological conditions is poorly understood and is limited to certain tissues and organisms. We hypothesized that CMNGE is important for development across vertebrates and, hence, should be conserved. As a first step, we analyzed more...
  5. Resource: Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging
    • Jacob C. Kimmel,
    • Lolita Penland,
    • Nimrod D. Rubinstein,
    • David G. Hendrickson,
    • David R. Kelley,
    • and Adam Z. Rosenthal
    Genome Res. December 2019 29: 2088-2103; Published in Advance November 21, 2019, doi:10.1101/gr.253880.119
    ...in the magnitude of change within multiple NMF dimensions (Fig. 5D). Based on Gene Ontology enrichment within these dimensions, endothelial/epithelial cell types showed an increase in thyroid hormone and type I interferon signaling (Dimension 2) (Fig. 5E) and a decrease in transcriptional machinery and cell cycle...
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  6. Method: Co-expression networks reveal the tissue-specific regulation of transcription and splicing
    • Ashis Saha,
    • Yungil Kim,
    • Ariel D.H. Gewirtz,
    • Brian Jo,
    • Chuan Gao,
    • Ian C. McDowell,
    • The GTEx Consortium,
    • Barbara E. Engelhardt,
    • and Alexis Battle
    Genome Res. November 2017 27: 1843-1858; Published in Advance October 11, 2017, doi:10.1101/gr.216721.116
    ..., a gene highly expressed in breast cancer (Liu et al. 2008). The second ranked hub gene for the tissue group including skeletal muscle and heart–left ventricle was LMOD2, which was observed to be abundantly expressed in both tissues and has been reported to regulate the thin filament length in muscles...
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  7. LETTER: Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster
    • Jian Chen,
    • Xiaoying Shi,
    • Ranjani Padmanabhan,
    • Qiong Wang,
    • Zhidan Wu,
    • Susan C. Stevenson,
    • Marc Hild,
    • Dan Garza,
    • and Hao Li
    Genome Res. January 2008 18: 123-136; Published in Advance November 27, 2007, doi:10.1101/gr.6940108
    ...CS activity in transgenic flies or fly mutants. We confirmed a number of gene hits including HDAC6 , Rpd3 ( HDAC1 ), CG3249 , vimar , Src42A , klumpfuss , barren , and smt3 which exert effects on mitochondrial CS activities in vivo, demonstrating the value of Drosophila genome-wide RNAi...
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