Searching journal content for articles similar to Chung et al. 21 (2): 286.

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  1. ...(Yang and Lai 2011). The most prevalent alternative pathway involves short hairpin introns known as mirtrons (Fig. 1) that serve as pre-miRNA mimics (Westholm and Lai 2011). The biochemical and functional properties of mirtrons have been studied most carefully in Drosophila (Okamura et al. 2007; Ruby et...
  2. ...studies show that miRNA subclasses exhibit distinct evolutionary parameters (Mohammed et al. 2013, 2014a,b). For example, mirtrons evolve more quickly than canonical miRNAs in both Drosophila (Berezikov et al. 2010) and in mammals (Wen et al. 2015), and studies in D. melanogaster identified...
  3. ...Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence Eugene Berezikov 1 , Nicolas Robine 2 , Anastasia Samsonova 3 , Jakub O. Westholm 2 , Ammar Naqvi 2 , Jui-Hung Hung...
  4. ...data provide comprehensive information on the transcriptional landscape of diverse Drosophila cell lines. These data should encourage broader usage of fly cell lines, beyond the few that are presently in common usage. [Supplemental material is available for this article.] Drosophila melanogaster...
  5. ...computational methods to predict miRNAs conserved among Drosophila species and large-scale sequencing of small RNAs from Drosophila melanogaster to experimentally confirm and complement these predictions. In addition to validating 20 of our top 45 predictions for novel miRNA loci, the large-scale sequencing...
  6. ...for their identification (Berezikov et al. 2006b). However, even when considering these additional novel nonconserved candidate miRNAs in C. elegans miRNAs, the miRNA birth rate in the nematodes would still appear to be three- to fourfold lower than in the Drosophila species. Comparison of miRNA expression levels between...
  7. ...be advantageous in an arms race against invading nucleic acids. We found that gonochoristic species that mate at every generation possess much larger numbers of piRNAs than androdioecious species that primarily self-fertilize. In Drosophila, maternally deposited piRNAs can silence paternal transposons (Brennecke...
  8. ...selected human and two animal models (mouse and Drosophila melanogaster [D.mel], in which the ADAR mutant phenotypes were extensively studied) for RNA editing profiling. A human–mouse comparison will shed light on the miRNA editing dynamics and evolution in mammals. Additionally, the miRNA editing profiles...
  9. ...sequenced inDrosophila,Caenorhabditis elegans, mouse oocytes, and embryonic stem cells, and most recently in Xenopus tropicalis (Hamilton and Baulcombe 1999; Ambros et al. 2003b; Babiarz et al. 2008; Czech et al. 2008;Watanabe et al. 2008; Armisen et al. 2009). In a number of organisms they have also been...
  10. ...miRNAs detected (Fig. 1B). This result is in contrast to the finding that the absolute numbers of expressed miRNAs increase over the developmental time in other model organisms such as Drosophila melanogaster (Ninova et al. 2014). At the organ level, we find that the nervous system samples show...
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