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Cho et al. 14 (7): 1207
.
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49
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Research
:
Pangenome analysis reveals families of ubiquitin-ligase adaptors as key genomic divergence drivers that lead to hybrid incompatibility
Dongying Xie
,
Pohao Ye
,
Yiming Ma
,
and
Zhongying Zhao
Genome Res.
March 2026
36
:
506
-
521
;
Published in Advance
February 17, 2026
,
doi:
10.1101/gr.280885.125
...studies may overlook. On the other hand, analyses of genomic variation
frequently
reveal
a complex interplay among sequence changes, including single-nucleotide polymorphisms (SNPs) and structural variations (SVs), which are associated with altered gene expression and phenotypic traits (Collins et al...
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:
Genetic exchange with an outcrossing sister species causes severe genome-wide dysregulation in a selfing
Caenorhabditis
nematode
Dongying Xie
,
Pohao Ye
,
Yiming Ma
,
Yongbin Li
,
Xiao Liu
,
Peter Sarkies
,
and
Zhongying Zhao
Genome Res.
November/December 2022
32
:
2015
-
2027
;
Published in Advance
November 9, 2022
,
doi:
10.1101/gr.277205.122
...
frequently
observed in hybrids (Wei et al. 2014; Lu et al. 2018; Moran et al. 2021). Notably, our previous study of hybrid sterile males between C. briggsae and C. nigoni, resulting from extensive backcrossing with C. nigoni, also
revealed
the dysregulation of spermatogenesis genes (Li et al. 2016b...
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Method
:
Nematode gene annotation by machine-learning-assisted proteotranscriptomics enables proteome-wide evolutionary analysis
Alejandro Ceron-Noriega
,
Miguel V. Almeida
,
Michal Levin
,
and
Falk Butter
Genome Res.
January 2023
33
:
112
-
128
;
Published in Advance
January 18, 2023
,
doi:
10.1101/gr.277070.122
...the gene tree that best represents the underlying alignment. These very solid orthology groups represent a highly useful resource for universal
nematode
analyses given that our study showed that the
frequently
used BUSCO set of single-copy orthologs does not really represent the common
nematode
proteome...
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Research
:
Transposable elements drive the evolution of metazoan zinc finger genes
Jonathan N. Wells
,
Ni-Chen Chang
,
John McCormick
,
Caitlyn Coleman
,
Nathalie Ramos
,
Bozhou Jin
,
and
Cédric Feschotte
Genome Res.
August 2023
33
:
1325
-
1339
;
Published in Advance
September 15, 2023
,
doi:
10.1101/gr.277966.123
.... 2019). Furthermore, they are
frequently
lineage-specific; for example, a survey of three great ape species and rhesus macaque found that ∼10% (213 out of 2253) of predicted KRAB-ZNFs (KZNFs) were species-specific, including seven from humans and 145 from orangutangs (Nowick et al. 2011). This rapid...
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Research
:
Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in
Drosophila melanogaster
Anna Grandchamp
,
Lucas Kühl
,
Marie Lebherz
,
Kathrin Brüggemann
,
John Parsch
,
and
Erich Bornberg-Bauer
Genome Res.
June 2023
33
:
872
-
890
;
Published in Advance
July 13, 2023
,
doi:
10.1101/gr.277482.122
...ORFs shared by lines, suggesting a rapid turnover. Gain and loss of transcription is more
frequent
than the creation of ORFs, for example, by forming new start and stop codons. Consequently, the gain of ORFs becomes rate limiting and is
frequently
the initial step in neORFs emergence. Furthermore...
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:
A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes
Stefanie Mühlhausen
,
Peggy Findeisen
,
Uwe Plessmann
,
Henning Urlaub
,
and
Martin Kollmar
Genome Res.
July 2016
26
:
945
-
955
;
Published in Advance
May 6, 2016
,
doi:
10.1101/gr.200931.115
..., including the branches with altered decoding. The polyphyly of the tRNALeuCAGs is not explained in either of the scenarios. The scenario of two successive CUG-codon reassignments is further weakened by the
frequent
nature of the CUG codon. Although phylogenetic mapping of variant codes has shown...
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Research
:
Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization
Marco Mariotti
,
Didac Santesmasses
,
Salvador Capella-Gutierrez
,
Andrea Mateo
,
Carme Arnan
,
Rory Johnson
,
Salvatore D'Aniello
,
Sun Hee Yim
,
Vadim N. Gladyshev
,
Florenci Serras
,
Montserrat Corominas
,
Toni Gabaldón
,
and
Roderic Guigó
Genome Res.
September 2015
25
:
1256
-
1267
;
Published in Advance
July 20, 2015
,
doi:
10.1101/gr.190538.115
...and the SECIS element degenerated. This exemplifies an evolutionary scenario, not
frequently
reported in the literature, in which alternative transcripts precede gene duplication, providing a possible intermediary step of how a dual-function protein can escape from adaptive conflict (Hittinger and Carroll 2007...
Abstract
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Research
:
Intron evolution in
Neurospora
: the role of mutational bias and selection
Yu Sun
,
Carrie A. Whittle
,
Pádraic Corcoran
,
and
Hanna Johannesson
Genome Res.
January 2015
25
:
100
-
110
;
Published in Advance
October 23, 2014
,
doi:
10.1101/gr.175653.114
...by homologous recombination (Bernstein et al. 1983; Lewin 1983; Boeke et al. 1985). Since reverse transcription is processed from 39 to 59, and often terminates prematurely,
intron
losses are expected to occur more
frequently
in the 39 end of the genes (Fink 1987; Mourier and Jeffares 2003). Nonetheless...
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LETTER
:
Evolutionary dynamics of nematode operons: Easy come, slow go
Wenfeng Qian
and
Jianzhi Zhang
Genome Res.
March 2008
18
:
412
-
421
;
Published in Advance
January 24, 2008
,
doi:
10.1101/gr.7112608
...mapped the operon gain and loss events onto the
nematode
phylogeny
( Fig. 1 ). From the common ancestor of the four
Caenorhabditis
species to present, 56 operons were formed in the C. elegans lineage. During the same period of time, on average, {[(17 + 12)/2 + 3]+16}/2 = 16.75 operons were broken per...
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LETTER
:
Evolution of Intron/Exon Structure of DEAD Helicase Family Genes in
Arabidopsis
,
Caenorhabditis
, and
Drosophila
Nathalie Boudet
,
Sébastien Aubourg
,
Claire Toffano-Nioche
,
Martin Kreis
,
and
Alain Lecharny
Genome Res.
December 1, 2001
11
:
2101
-
2114
;
Published in Advance
November 12, 2001
,
doi:
10.1101/gr.200801
...
Evolution
of
Intron
/Exon Structure of DEAD Helicase Family Genes in Arabidopsis ,
Caenorhabditis
, and Drosophila Nathalie Boudet 1 , Sébastien Aubourg 1 , 2 , Claire Toffano-Nioche 1 , Martin Kreis 1 , and Alain Lecharny 1 , 3...
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