Searching journal content for articles similar to Chiu et al. 25 (2): 257.

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  1. ...1Scalable cell-specific coexpression networks for granular regulatory 2 pattern discovery with NeighbourNet 3 Yidi Deng1,2, Jiadong Mao1,† & Jarny Choi3,† & Kim-Anh Lê Cao1,*,† 4 1Melbourne Integrative Genomics, School of Mathematics and Statistics, The University of Melbourne, 5 3010, Australia 6...
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  2. ...55421, USA Corresponding author: jshaw@ds.dfci.harvard.eduAbstractReconstructing exact haplotypes is important when sequencing a mixture of similar sequences. Long-read sequencing can connect distant alleles to disentangle similar haplotypes, but handling sequencing errors requires specialized...
  3. ...as a multislice joint analysis framework featuring a precorrection mechanism that enables the precise identification of complex spatial domains, advancing disease pathology insights. STMSC assumes that precise three-dimensional (3D) reconstruction is essential for an in-depth investigation of tissue components...
  4. ...in microRNA target identification Genome Research 237 www..org observed decrease in target mRNAs upon ceRNA knock-down. Consequently, the consensus now states that mRNAs are unlikely to exert any noticeable titration of miRNAs in the general case (Garcia et al. 2011; Wee et al. 2012; Denzler et al. 2014...
  5. ..., reconstructing cell type–specific networks and allowing in silico T perturbations to reveal dynamic regulatory mechanisms. The knowledge-primed model SupirFactor (Tjärnberg et al. 2024) embeds the prior GRN directly into deep learning architectures, enabling biologically interpretable GRN predictions while...
  6. ....uni-wuerzburg.de, shaocw@ysfri.ac.cnAbstractCompeting endogenous RNAs (ceRNAs) are vital regulators of gene networks in mammals. The involvement of noncoding RNAs (ncRNAs) as ceRNA in genotypic sex determination (GSD) and environmental sex determination (ESD) in fish is unknown. The Chinese tongue sole, which has both GSD...
  7. ...provide insights into processes that are simultaneously activated in different biological states (Becker et al. 2023). However, most methods for constructing coexpression networks estimate an aggregate network for the entire population (Langfelder and Horvath 2008; Dawson et al. 2012; Lemoine et al. 2021...
  8. ...of correlation in spatial transcriptomics data by extending the concept of CI to spatially distributed information, facilitating the reconstruction of both the intracellular and the intercellular interaction networks with single-cell spatial resolution. SpaCeNet was developed to address the diversity of cellular...
  9. ...space modeling, DigNet is robust to the presence of noise in scRNA-seq data and the sparsity of GRNs. Benchmark evaluation results against more than a dozen state-of-the-art network inference methods demonstrate that DigNet achieves superior performance across various single-cell GRN reconstruction...
  10. ...identification within a large, complex cell population. In this study, we developed a subclone clustering method based on a fused lasso model, referred to as FLCNA, which can simultaneously detect CNAs in single-cell DNA sequencing (scDNA-seq) data. Spike-in simulations were conducted to evaluate the clustering...
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