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LETTER: Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes
- Anne-Sophie Van Laere,
- Wouter Coppieters,
- and Michel Georges
Genome Res. December 2008 18: 1884-1895; Published in Advance November 3, 2008, doi:10.1101/gr.082487.108
...recently acquired by the Y by means of LINE-mediated illegitimate recombination ( Charchar et al. 2003 ). The recombination rate in PAR2 is reportedly much lower than in PAR1 ( Lien et al. 2000 ). Extant and ancestral pseudoautosomal boundaries (PABs) To the best of our knowledge, extant PABs have only...
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LETTER: A Short Pseudoautosomal Region in Laboratory Mice
- Jo Perry,
- Steve Palmer,
- Anastasia Gabriel,
- and Alan Ashworth
Genome Res. November 1, 2001 11: 1826-1832; doi:10.1101/gr.203001
...Abstract The pseudoautosomal region (PAR) of mammalian sex chromosomes is a small region of sequence identity that is the site of an obligatory pairing and recombination event between the X and Y chromosomes during male meiosis. During female meiosis, X chromosomes can pair and recombine along...
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LETTER: Differential Divergence of Three Human Pseudoautosomal Genes and Their Mouse Homologs: Implications for Sex Chromosome Evolution
- Fernando Gianfrancesco,
- Remo Sanges,
- Teresa Esposito,
- Sergio Tempesta,
- Ercole Rao,
- Gudrun Rappold,
- Nicoletta Archidiacono,
- Jennifer A.M. Graves,
- Antonino Forabosco,
- and Michele D'Urso
Genome Res. December 1, 2001 11: 2095-2100; doi:10.1101/gr.197001
.../or selection at linked loci on the Y ( Charlesworth 1990 ). However, pseudoautosomal regions 1 and 2 (PAR1 and PAR2) at the termini of the short and long arms of X and Y chromosomes still recombine during male meiosis, ensuring X-Y nucleotide sequence identity that is necessary for normal male meiosis...
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LETTER: Recombination Has Little Effect on the Rate of Sequence Divergence in Pseudoautosomal Boundary 1 Among Humans and Great Apes
- Soojin Yi,
- Tyrone J. Summers,
- Nathaniel M. Pearson,
- and Wen-Hsiung Li
Genome Res. January 2004 14: 37-43; Published in Advance December 12, 2003, doi:10.1101/gr.1777204
..., M., El-Mogharbel, N., Ventura, M., Kirby, P., Matarazzo, M.R., Ciccodicola, A., Rocchi, M., D'Esposito, M., and Graves, J.A. 2003 . Complex events in the evolution of the human PAR2. Genome Res. 13 : 281 -286. ↵ Chen, F.-C. and Li, W.-H. 2001 . Genomic divergences between humans and other hominoids...
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LETTER: Centromere Emergence in Evolution
- Mario Ventura,
- Nicoletta Archidiacono,
- and Mariano Rocchi
Genome Res. April 1, 2001 11: 595-599; doi:10.1101/gr.152101
...Region 1 (PAR1) and mapping 80 to 110 kb from Xpter ( Gianfrancesco et al. 1998 ), was used as a telomeric Xp marker. A cosmid clone (U130F6) containing the HSPRY3 gene was used as a marker of the Xqter region. HSPRY3 maps inside the PAR2, approximately 250 kb from the Xq telomere ( Ciccodicola et al...
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Research: Quantitative analysis of Y-Chromosome gene expression across 36 human tissues
- Alexander K. Godfrey,
- Sahin Naqvi,
- Lukáš Chmátal,
- Joel M. Chick,
- Richard N. Mitchell,
- Steven P. Gygi,
- Helen Skaletsky,
- and David C. Page
Genome Res. June 2020 30: 860-873; Published in Advance May 27, 2020, doi:10.1101/gr.261248.120
...of the two pseudoautosomal regions (PAR1, PAR2), the X and Y Chromosomes have diverged in sequence. The locations of protein-coding genes and multicopy gene families in the male-specific region of the human Y Chromosome (MSY; blue) are shown at right. The X-linked homologs of MSY genes are annotated...
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Method: Characterizing polymorphic inversions in human genomes by single-cell sequencing
- Ashley D. Sanders,
- Mark Hills,
- David Porubský,
- Victor Guryev,
- Ester Falconer,
- and Peter M. Lansdorp
Genome Res. November 2016 26: 1575-1587; Published in Advance July 29, 2016, doi:10.1101/gr.201160.115
...of these approaches limits their application tomapping largemicroscopic events that disrupt visible patterns (typically at the megabase-scale), and their low throughput limits the number of cells or individuals that can be studied at a time (Youings et al. 2004; Zody et al. 2008; Antonacci et al. 2009; Feuk 2010...
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LETTER: Evolutionary dynamics of segmental duplications from human Y-chromosomal euchromatin/heterochromatin transition regions
- Stefan Kirsch,
- Claudia Münch,
- Zhaoshi Jiang,
- Ze Cheng,
- Lin Chen,
- Christiane Batz,
- Evan E. Eichler,
- and Werner Schempp
Genome Res. July 2008 18: 1030-1042; Published in Advance April 29, 2008, doi:10.1101/gr.076711.108
.... In contrast, duplicons from the Yq11.1/Yq11.21, Yq11.23/Yq12, and Yq12/PAR2 regions show no evidence of duplication in rhesus macaque, but map to the pericentromeric regions in chimpanzee and human. This suggests an evolutionary shift in the direction of duplicative transposition events from subtelomeric...

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