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Research: Regulation of nucleosome positioning by a CHD Type III chromatin remodeler and its relationship to developmental gene expression in Dictyostelium
- James L. Platt,
- Nicholas A. Kent,
- Alan R. Kimmel,
- and Adrian J. Harwood
Genome Res. April 2017 27: 591-600; Published in Advance March 22, 2017, doi:10.1101/gr.216309.116
...to investigate CHD Type III remodeling proteins in the context of developmental regulation of nucleosome positioning and gene expression. Previous nucleosome mapping of Dictyostelium chromatin focused on ∼40% of the and suggested an organization similar to that of multicellular animals, with little overall...
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Research: DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome
- Leslie Y. Beh,
- Manuel M. Müller,
- Tom W. Muir,
- Noam Kaplan,
- and Laura F. Landweber
Genome Res. November 2015 25: 1727-1738; Published in Advance September 1, 2015, doi:10.1101/gr.188516.114
...of eukaryotic chromatin. Each nucleosome consists of ∼147 bp of DNAwrapped around a histone octamer (Luger et al. 1997). The organization of nucleosomes across the plays an important regulatory role as it lowers the physical accessibility of DNA to cellular factors and may directly impact DNA-based transactions...

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