Searching journal content for articles similar to Chance et al. 14 (10b): 2145.

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  1. ..., Germany; 12Department of Statistical Bioinformatics, University of Regensburg, 93053 Regensburg, Germany ↵13 These authors contributed equally to this work. Corresponding author: robin.kosch@protonmail.comAbstractHigh-throughput bottom-up proteomic data cover thousands of proteins and related co- and post...
  2. ...structure analyses, genetic diversity evaluation, and ancestry estimation (Kennedy et al. 2003; Zimmerman et al. 2020). Simultaneously, the latest advances in SNP high-throughput arrays and WGS facilitate the SNPs applied in the usual genetic analyses. However, compared with WGS, SNP arrays were primarily...
  3. ....delledonne@univr.it, r.papa@staff.univpm.itAbstractHigh-throughput genotyping enables the large-scale analysis of genetic diversity in population genomics and -wide association studies that combine the genotypic and phenotypic characterization of large collections of accessions. Sequencing-based approaches...
  4. ...insights into the origins of human diseases. However, epigenomic data, such as chromatin accessibility and histone modifications, enhance the dynamic characteristics of CREs to gene regulation, making it more challenging to decipher the relationships between CREs and gene expression.High-throughput...
  5. ...available s displays a wonderful diversity in size, composition, and structure and is quickly expanding thanks to several global biodiversity genomics initiatives. However, sequencing of s, even with the latest technologies, can still be challenging for both technical (e.g., small physical size...
  6. ...biological functions (Le and Maizel 1997; Cheng et al. 2001). The VAE-GMM k-mer clustering model, by combining deep neural networks with probabilistic clustering and dimensionality reduction techniques, offers a promising framework for decoding high-dimensional RNA sequence structures and uncovering latent...
  7. .... An in vitro CRISPR/Cas9 RNA-directed nickase system directs the specific labeling of human (TTAGGG)n DNA tracts in s that have also been barcoded using a separate nickase enzyme that recognizes a 7bp motif -wide. High-throughput imaging and analysis of large DNA single molecules from s labeled in this fashion...
  8. ....3% of the UCYN-A1 (Fig. 5). The estimated completeness of the UCYN-A computed based on a set of 139 bacterial-specific single-copy core genes (Campbell et al. 2013) was 82.7% for MGT-29 and 42.4% for MGT-176. The ANI value between MGT-29 and UCYN-A1 isolate ALOHA was 99.7%, which indicates a high genomic...
  9. ...the effect of perturbations in humans to improve health will require an unmasking of the complex regulation of the cell and improved understanding of how cell interactions shape human physiology.The advent of high-throughput single-cell genomics technologies has brought the scientific community one step...
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  10. ...monomers and dimers removed with a second set of SPRI bead treatment in preparation for high-throughput sequencing (Methods).View larger version: In this window In a new window Figure 1. Schematic representation of overall workflow and quality control of snCUT&RUN. (A) Schematic overview of sn...
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