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LETTER: Comparative Genome Analysis of the Primary Sex-Determining Locus in Salmonid Fishes
- Rachael A. Woram,
- Karim Gharbi,
- Takashi Sakamoto,
- Bjorn Hoyheim,
- Lars-Erik Holm,
- Kerry Naish,
- Colin McGowan,
- Moira M. Ferguson,
- Ruth B. Phillips,
- Jake Stein,
- René Guyomard,
- Margaret Cairney,
- John B. Taggart,
- Richard Powell,
- William Davidson,
- and Roy G. Danzmann
Genome Res. February 1, 2003 13: 272-280; doi:10.1101/gr.578503
...molecular markers. Our results confirm and extend preliminary observations indicating that the sex-determining locus is not conserved with respect to synteny with identified homologous chromosome sets among these various species. RESULTS Sex Linkage of Molecular Markers Gene mapping in Arctic charr (data...
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ARTICLE: Interchromosomal segmental duplications of the pericentromeric region on the human Y chromosome
- Stefan Kirsch,
- Birgit Weiß,
- Tracie L. Miner,
- Robert H. Waterston,
- Royden A. Clark,
- Evan E. Eichler,
- Claudia Münch,
- Werner Schempp,
- and Gudrun Rappold
Genome Res. February 2005 15: 195-204; Published in Advance January 14, 2005, doi:10.1101/gr.3302705
...been mapped to chromosomes 10, 13, 14, 15, 21, and 22 in the meantime. Proof of active transcription of the DUX genes has been provided for six family members (DUX1-5, -10). Similar to DUX2, none of the four Y-chromosomal DUX copies preserves a complete second homeodomain. Nevertheless, the high...
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LETTER: A Physical Map of the Leishmania majorFriedlin Genome
- Alasdair C. Ivens,
- Sharon M. Lewis,
- Azadeh Bagherzadeh,
- Linglan Zhang,
- Ho M. Chan,
- and Deborah F. Smith
Genome Res. February 1, 1998 8: 135-145; doi:10.1101/gr.8.2.135
...effects: (1) These clones were not placed into contigs because of the probability cutoff used; and (2) contigs constructed manually from these clones resulted in an incorrect estimate of contig size. As an example, the miniexon gene locus, mapped to chromosome 2, is known to consist of a tandem array...
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ARTICLE: Generation of a transcriptional map for a 700-kb region surrounding the polycystic kidney disease type 1 (PKD1) and tuberous sclerosis type 2 (TSC2) disease genes on human chromosome 16p3.3.
- T C Burn,
- T D Connors,
- T J Van Raay,
- W R Dackowski,
- J M Millholland,
- K W Klinger,
- and G M Landes
Genome Res. June 1996 6: 525-537; doi:10.1101/gr.6.6.525
....P. et al. 1995 . Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17. Genomics 25 : 238 – 247 . Brown, M.A., , Jones, K.A. , Nicolai, H. , Bonjardim, M. , Black, D. , Mcfarlane, R. , Dejong, P. , Quirk, J.P. , Lehrach, H. , Solomon. E. Brown, M.A., Jones, K.A. Nicolai...
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Research: Extreme genome scrambling in marine planktonic Oikopleura dioica cryptic species
- Charles Plessy,
- Michael J. Mansfield,
- Aleksandra Bliznina,
- Aki Masunaga,
- Charlotte West,
- Yongkai Tan,
- Andrew W. Liu,
- Jan Grašič,
- María Sara del Río Pisula,
- Gaspar Sánchez-Serna,
- Marc Fabrega-Torrus,
- Alfonso Ferrández-Roldán,
- Vittoria Roncalli,
- Pavla Navratilova,
- Eric M. Thompson,
- Takeshi Onuma,
- Hiroki Nishida,
- Cristian Cañestro,
- and Nicholas M. Luscombe
Genome Res. March 2024 34: 426-440; Published in Advance April 15, 2024, doi:10.1101/gr.278295.123
...blocks (e.g., MyhF, MyhG, Fgf11/12/13/14a, Fgf11/12/13/14b, and Hox1) to situations in which a block has seemingly fragmented into many small pieces (e.g., Fgf9/16/20a and Hox10 or Hox12). Based on our examination of chromosome mapping for different conserved gene families in O. dioica, the position...
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Mini-Review: Toward telomere-to-telomere cat genomes for precision medicine and conservation biology
- William J. Murphy and
- Andrew J. Harris
Genome Res. May 2024 34: 655-664; Published in Advance June 7, 2024, doi:10.1101/gr.278546.123
...into structure and chromosome evolution through comparative genomics and recent success stories using genotype-to-phenotype mapping to clarify the basis for feline traits and species evolution. Lastly, we will explore the potential for discovering and applying genomic evidence to the management and conservation...
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Resource: Assembly of a pangenome for global cattle reveals missing sequences and novel structural variations, providing new insights into their diversity and evolutionary history
- Yang Zhou,
- Lv Yang,
- Xiaotao Han,
- Jiazheng Han,
- Yan Hu,
- Fan Li,
- Han Xia,
- Lingwei Peng,
- Clarissa Boschiero,
- Benjamin D. Rosen,
- Derek M. Bickhart,
- Shujun Zhang,
- Aizhen Guo,
- Curtis P. Van Tassell,
- Timothy P.L. Smith,
- Liguo Yang,
- and George E. Liu
Genome Res. August 2022 32: 1585-1601; Published in Advance August 17, 2022, doi:10.1101/gr.276550.122
.... The identification of EST and associated transcripts provided the third way to roughly localize additional 27 representative contigs on the ARS-UCD1.2 assembly with relatively low precision. Combining the read pair, alternate assembly, and EST strategies for determining the chromosomal position of novel segments, we...
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Research: Reactivation of transposable elements following hybridization in fission yeast
- Sergio Tusso,
- Fang Suo,
- Yue Liang,
- Li-Lin Du,
- and Jochen B.W. Wolf
Genome Res. February 2022 32: 324-336; Published in Advance December 14, 2021, doi:10.1101/gr.276056.121
...samples corresponding to 31 nonclonal haploid S. pombe strains. (A) Heat map representing SNP-based haplotypes across all three chromosomes (I, II, and III) for the 38 samples used in this study. Six clonal samples derived from the same strain are indicated by vertical bars. Haplotypes are painted by Sp...
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Research: Long terminal repeats power evolution of genes and gene expression programs in mammalian oocytes and zygotes
- Vedran Franke,
- Sravya Ganesh,
- Rosa Karlic,
- Radek Malik,
- Josef Pasulka,
- Filip Horvat,
- Maja Kuzman,
- Helena Fulka,
- Marketa Cernohorska,
- Jana Urbanova,
- Eliska Svobodova,
- Jun Ma,
- Yutaka Suzuki,
- Fugaku Aoki,
- Richard M. Schultz,
- Kristian Vlahovicek,
- and Petr Svoboda
Genome Res. August 2017 27: 1384-1394; Published in Advance May 18, 2017, doi:10.1101/gr.216150.116
...not be determined from the data. A lower but apparent transcript accumulation was also found downstream from ORR1A and MT2 solo LTRs that are less expressed during ZGA (Supplemental Fig. S5C,D). Novel multiexon lncRNA genes may emerge by deploying an ERVL LTR into a new genomic locus. Of the 333 lncRNA loci co...
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REVIEW: Genomics and Hearing Impairment
- Bronya J. B. Keats and
- Charles I. Berlin
Genome Res. January 1, 1999 9: 7-16; doi:10.1101/gr.9.1.7
...affected individuals had normal hearing until ∼10 yr of age but the loss became profound within 4–5 yr ( Veske et al. 1996 ). This locus ( DFNB8 ) was mapped to the long arm of chromosome 21. In general, loci for hearing impairment in unrelated families have been mapped to different chromosomal regions...

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