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Method: Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data using universal protein motifs
- Sara Silva Pereira,
- Aitor Casas-Sánchez,
- Lee R. Haines,
- Moses Ogugo,
- Kihara Absolomon,
- Mandy Sanders,
- Steve Kemp,
- Álvaro Acosta-Serrano,
- Harry Noyes,
- Matthew Berriman,
- and Andrew P. Jackson
Genome Res. September 2018 28: 1383-1394; Published in Advance July 13, 2018, doi:10.1101/gr.234146.118
...of labeling errors can never be ruled out, we are confident that the association between the VAP and population structure is genuinely weak. African trypanosome s include extended subtelomeric domains that contain large numbers of VSG and other multicopy gene families and are distinct from chromosomal “cores...
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LETTER: Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure
- Lucio Marcello and
- J. David Barry
Genome Res. September 2007 17: 1344-1352; Published in Advance July 25, 2007, doi:10.1101/gr.6421207
.... ( 2006 ) Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length . Genome Res. 16 : 1109 – 1118 . ↵ Campillo, N. , Carrington, M. ( 2003 ) The origin of the serum resistance associated (SRA) gene and a model of the structure of the SRA polypeptide from...

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