Searching journal content for articles similar to Brockmann et al. 10 (12): 1941.

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  1. LETTER: A Global Search Reveals Epistatic Interaction Between QTL for Early Growth in the Chicken
    • Örjan Carlborg,
    • Susanne Kerje,
    • Karin Schütz,
    • Lina Jacobsson,
    • Per Jensen,
    • and Leif Andersson
    Genome Res. March 1, 2003 13: 413-421; doi:10.1101/gr.528003
    .... , Haley C.S. , Renne U. , Schwerin M. , Karle S. ( 2000 ) Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F2 variance of growth and obesity in DU6I × DBA/2 mice. Genome Res. 10 : 1941 – 1957 . ↵ Carlborg Ö. , Andersson L. ( 2002 ) The use of randomization testing...
  2. Perspective: Genetic architecture of quantitative traits in mice, flies, and humans
    • Jonathan Flint and
    • Trudy F.C. Mackay
    Genome Res. May 2009 19: 723-733; doi:10.1101/gr.086660.108
    ...in rodents). Remarkably, the picture that emerged from both organisms was broadly similar. Most of the early mapping studies revealed that a few QTLs with relatively large effects accounted for the bulk of phenotypic variation in most traits. This observation was central to driving attempts to capture common...
  3. LETTER: Voluntary Ethanol Consumption by Mice: Genome-Wide Analysis of Quantitative Trait Loci and Their Interactions in a C57BL/6ByJ × 129P3/J F2 Intercross
    • Alexander A. Bachmanov,
    • Danielle R. Reed,
    • Xia Li,
    • Shanru Li,
    • Gary K. Beauchamp,
    • and Michael G. Tordoff
    Genome Res. August 1, 2002 12: 1257-1268; doi:10.1101/gr.129702
    ...higher statistical power to detect B6-recessive loci compared with F2 intercross; this also may account for differences in identified sets of loci. Age potentially can modify the effects of alcohol-related QTL ( McClearn et al. 1998 ). In most ethanol preference QTL studies, ∼2–3-month-old mice were...
  4. Research: Genetic analysis of complex traits in the emerging Collaborative Cross
    • David L. Aylor,
    • William Valdar,
    • Wendy Foulds-Mathes,
    • Ryan J. Buus,
    • Ricardo A. Verdugo,
    • Ralph S. Baric,
    • Martin T. Ferris,
    • Jeff A. Frelinger,
    • Mark Heise,
    • Matt B. Frieman,
    • Lisa E. Gralinski,
    • Timothy A. Bell,
    • John D. Didion,
    • Kunjie Hua,
    • Derrick L. Nehrenberg,
    • Christine L. Powell,
    • Jill Steigerwalt,
    • Yuying Xie,
    • Samir N.P. Kelada,
    • Francis S. Collins,
    • Ivana V. Yang,
    • David A. Schwartz,
    • Lisa A. Branstetter,
    • Elissa J. Chesler,
    • Darla R. Miller,
    • Jason Spence,
    • Eric Yi Liu,
    • Leonard McMillan,
    • Abhishek Sarkar,
    • Jeremy Wang,
    • Wei Wang,
    • Qi Zhang,
    • Karl W. Broman,
    • Ron Korstanje,
    • Caroline Durrant,
    • Richard Mott,
    • Fuad A. Iraqi,
    • Daniel Pomp,
    • David Threadgill,
    • Fernando Pardo-Manuel de Villena,
    • and Gary A. Churchill
    Genome Res. August 2011 21: 1213-1222; Published in Advance March 15, 2011, doi:10.1101/gr.111310.110
    ...QTLs discovered here exceeds all previous efforts at eQTL mapping in mice, and we map local eQTL at 1-Mb resolution. We demonstrate that the genetic diversity of the CC, which derives from randommixing of eight founder strains, results in high phenotypic diversity and enhances our ability to map...
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