Searching journal content for articles similar to Brinkman et al. 22 (6): 1128.

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  1. Research: Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms
    • Franck Court,
    • Elisa Le Boiteux,
    • Anne Fogli,
    • Mélanie Müller-Barthélémy,
    • Catherine Vaurs-Barrière,
    • Emmanuel Chautard,
    • Bruno Pereira,
    • Julian Biau,
    • Jean-Louis Kemeny,
    • Toufic Khalil,
    • Lucie Karayan-Tapon,
    • Pierre Verrelle,
    • and Philippe Arnaud
    Genome Res. October 2019 29: 1605-1621; Published in Advance September 18, 2019, doi:10.1101/gr.249219.119
    ...that most transcriptional alterations in tumor samples were DNA methylation–independent. Instead, altered histone H3 trimethylation at lysine 27 (H3K27me3) was the predominant molecular defect at deregulated genes. Our results also suggest that the presence of a bivalent chromatin signature at CpG island...
  2. Resource: Dynamic DNA methylation across diverse human cell lines and tissues
    • Katherine E. Varley,
    • Jason Gertz,
    • Kevin M. Bowling,
    • Stephanie L. Parker,
    • Timothy E. Reddy,
    • Florencia Pauli-Behn,
    • Marie K. Cross,
    • Brian A. Williams,
    • John A. Stamatoyannopoulos,
    • Gregory E. Crawford,
    • Devin M. Absher,
    • Barbara J. Wold,
    • and Richard M. Myers
    Genome Res. March 2013 23: 555-567; Published in Advance January 16, 2013, doi:10.1101/gr.147942.112
    ...sequencing provides the most direct and highest resolution method to quantify DNA methylation in the , enabling the ability to calculate the fraction of molecules that are methylated at each individual cytosine sequenced (Frommer et al. 1992). The advent of nextgeneration DNA sequencing technologies has...
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