Searching journal content for articles similar to Braunschweig et al. 24 (11): 1774.

Displaying results 1-10 of 32

For checked items

view abstracts
download to citation manager

Select this article
Research: Systematic identification and characterization of exon–intron circRNAs
- Yinchun Zhong,
- Yan Yang,
- Xiaolin Wang,
- Bingbing Ren,
- Xueren Wang,
- Ge Shan,
- and Liang Chen
Genome Res. March 2024 34: 376-393; Published in Advance April 12, 2024, doi:10.1101/gr.278590.123
...of the production of EIciRNAs versus that of EcircRNAs during backsplicing.As a type of AS, IR in linear transcripts is widespread in the transcriptome and can regulate gene expression in mammalian cells (Braunschweig et al. 2014; Monteuuis et al. 2019; Yeom et al. 2021; Wong and Schmitz 2022). The major features...
OPEN ACCESS ARTICLE
Select this article
Research: RNA Pol II–dependent transcription efficiency fine-tunes A-to-I editing levels
- Brigitta Szabo,
- Therese C. Mandl,
- Bernhard Woldrich,
- Gregor Diensthuber,
- David Martin,
- Michael F. Jantsch,
- and Konstantin Licht
Genome Res. February 2024 34: 231-242; Published in Advance March 12, 2024, doi:10.1101/gr.277686.123
...University of Vienna, A-1090 Vienna, Austria Corresponding authors: konstantin_licht@gmx.de, michael.jantsch@meduniwien.ac.atAbstractA-to-I RNA editing is a widespread epitranscriptomic phenomenon leading to the conversion of adenosines to inosines, which are primarily interpreted as guanosines by cellular...
OPEN ACCESS ARTICLE
Select this article
Resource: Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring
- Kyu-Hyeon Yeom,
- Zhicheng Pan,
- Chia-Ho Lin,
- Han Young Lim,
- Wen Xiao,
- Yi Xing,
- and Douglas L. Black
Genome Res. June 2021 31: 1106-1119; Published in Advance April 8, 2021, doi:10.1101/gr.273904.120
.... The nearby intron 1 (I1) was maintained as a Group A intron in all three cell types. Med22 encodes a subunit of the transcriptional mediator complex. The retention or splicing of Med22 I3 creates MED22 proteins with different C-terminal peptides that likely alter mediator function in the two cell types...
Select this article
Research: Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis
- Marija Petrić Howe,
- Hamish Crerar,
- Jacob Neeves,
- Jasmine Harley,
- Giulia E. Tyzack,
- Pierre Klein,
- Andres Ramos,
- Rickie Patani,
- and Raphaëlle Luisier
Genome Res. October 2022 32: 1808-1825; Published in Advance September 30, 2022, doi:10.1101/gr.276898.122
...in mammalian systems and for a long time was mostly considered as a product of inefficient or erroneous splicing. With advances in detection strategies, IR is now recognized as a more widespread and regulated process than previously thought, and the idea that IR could even functionally modulate cellular...
OPEN ACCESS ARTICLE
Select this article
Research: Widespread association of the Argonaute protein AGO2 with meiotic chromatin suggests a distinct nuclear function in mammalian male reproduction
- Kimberly N. Griffin,
- Benjamin William Walters,
- Haixin Li,
- Huafeng Wang,
- Giulia Biancon,
- Toma Tebaldi,
- Carolyn B. Kaya,
- Jean Kanyo,
- TuKiet T. Lam,
- Andy L. Cox,
- Stephanie Halene,
- Jean-Ju Chung,
- and Bluma J. Lesch
Genome Res. September 2022 32: 1655-1668; Published in Advance September 15, 2022, doi:10.1101/gr.276578.122
...total sperm count, and impaired offspring viability. We propose a model (Fig. 6) in which AGO2 undergoes widespread, transient recruitment to active euchromatin, binds nearby nascent transcripts, and selectively promotes their stabilization and export from the nucleus. This function enhances expression...
Select this article
Research: Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation
- Amanda J. Price,
- Taeyoung Hwang,
- Ran Tao,
- Emily E. Burke,
- Anandita Rajpurohit,
- Joo Heon Shin,
- Thomas M. Hyde,
- Joel E. Kleinman,
- Andrew E. Jaffe,
- and Daniel R. Weinberger
Genome Res. January 2020 30: 1-11; Published in Advance December 18, 2019, doi:10.1101/gr.250217.119
...than 47 times more genes differentially expressed by fraction in adult than prenatal cortex in poly(A)+ samples. Transcription has been shown previously to be more widespread in prenatal brain than at more mature time points, with 4.1% of the prenatal transcribed compared to 3.1% of the adult (Jaffe et...
Select this article
Method: Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome
- Hagen Tilgner,
- Fereshteh Jahanbani,
- Ishaan Gupta,
- Paul Collier,
- Eric Wei,
- Morten Rasmussen,
- and Michael Snyder
Genome Res. February 2018 28: 231-242; Published in Advance December 1, 2017, doi:10.1101/gr.230516.117
..., involving initial and terminal exons. Our results provide a more comprehensive understanding of the human transcriptome and a general, cost-effective method to analyze it.RNA molecules carry information from the to produce the cell's functional machines, proteins, or act directly, for example, as long...
OPEN ACCESS ARTICLE
Select this article
Research: Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation
- Maria Warnefors,
- Katharina Mössinger,
- Jean Halbert,
- Tania Studer,
- John L. VandeBerg,
- Isa Lindgren,
- Amir Fallahshahroudi,
- Per Jensen,
- and Henrik Kaessmann
Genome Res. December 2017 27: 1961-1973; Published in Advance October 27, 2017, doi:10.1101/gr.225391.117
...; Nothnick et al. 2010), suggesting an additional layer of post-transcriptional, sex-biased regulation.Taken together, previous studies suggest that sex-biased miRNA expression might be widespread and have potentially profound functional implications. Even so, previous efforts to identify sex-biased mi...
OPEN ACCESS ARTICLE
Select this article
Research: Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast
- Danny A. Bitton,
- Sophie R. Atkinson,
- Charalampos Rallis,
- Graeme C. Smith,
- David A. Ellis,
- Yuan Y.C. Chen,
- Michal Malecki,
- Sandra Codlin,
- Jean-François Lemay,
- Cristina Cotobal,
- François Bachand,
- Samuel Marguerat,
- Juan Mata,
- and Jürg Bähler
Genome Res. June 2015 25: 884-896; Published in Advance April 16, 2015, doi:10.1101/gr.185371.114
..., or bioinformatics noise, although a few might become stabilized during quiescence and in splicing-deficient cells. Widespread cryptic splice sites and novel introns Exon skipping represents only one mechanism by which alternative splice variants could be generated; additional mechanisms are intron retention...
OPEN ACCESS ARTICLE
Select this article
Research: Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans
- Bina Koterniak,
- Pallavi P. Pilaka,
- Xicotencatl Gracida,
- Lisa-Marie Schneider,
- Iva Pritišanac,
- Yun Zhang,
- and John A. Calarco
Genome Res. December 2020 30: 1766-1780; Published in Advance October 30, 2020, doi:10.1101/gr.267328.120
.... These alternative splicing events are distributed across five major classes: cassette type (exon skipping), alternative 3′ or 5′ splice site usage, alternative start or terminal exons, intron retention, and mutually exclusive splicing (Fig. 3A; Supplemental Fig. S3; Supplemental Table S3). We also identified...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Braunschweig et al. 24 (11): 1774.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: