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Research: Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation
- Ofir Hakim,
- Myong-Hee Sung,
- Shingo Nakayamada,
- Ty C. Voss,
- Songjoon Baek,
- and Gordon L. Hager
Genome Res. March 2013 23: 462-472; Published in Advance December 3, 2012, doi:10.1101/gr.147652.112
...architecture during T-cell functional differentiation Ofir Hakim,1,3,4,5 Myong-Hee Sung,1,4 Shingo Nakayamada,2 Ty C. Voss,1 Songjoon Baek,1 and Gordon L. Hager1,5 1Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA; 2...
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LETTER: Genomic Analysis of the Olfactory Receptor Region of the Mouse and Human T-Cell Receptor α/δ Loci
- Robert P. Lane,
- Jared C. Roach,
- Inyoul Y. Lee,
- Cecilie Boysen,
- Arian Smit,
- Barbara J. Trask,
- and Leroy Hood
Genome Res. January 1, 2002 12: 81-87; doi:10.1101/gr.197901
...) Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones. Genome Res. 7 : 330 – 338 . ↵ Buck L. , Axel R. ( 1991 ) A novel multigene family may encode odorant receptors, a molecular basis for odor recognition. Cell 65 : 165 – 187 . ↵ Bulger M. , Bender M...
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REPORT: Genomic Organization of the Dog Dystroglycan Gene DAG1 Locus on Chromosome 20q15.1–q15.2
- Tosso Leeb,
- Stephan Neumann,
- Alexandra Deppe,
- Matthew Breen,
- and Bertram Brenig
Genome Res. March 1, 2000 10: 295-301; doi:10.1101/gr.10.3.295
...membranes (Henry and Campbell 1998). The protein received additional attention as it serves as a receptor for viral and bacterial pathogens (Cao et al. 1998; Rambukkana et al. 1998). Dystroglycan consists of two subunits, termed aand b-dystroglycan. The two subunits are encoded by a single gene and arise...
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RESOURCE: Conditionally Amplifiable BACs: Switching From Single-Copy to High-Copy Vectors and Genomic Clones
- Jadwiga Wild,
- Zdenka Hradecna,
- and Waclaw Szybalski
Genome Res. September 1, 2002 12: 1434-1444; doi:10.1101/gr.130502
...: 69 – 79 . ↵ Boysen C. , Simon M.I. , Hood L. ( 1997 ) Analysis of the 1.1-Mb human α/δ T-cell receptor locus with bacterial artificial chromosome clones. Genome Res. 7 : 330 – 338 . ↵ Cai L. , Taylor J.F. , Wing R.A. , Gallagher D.S. , Woo S.S. , Davis S.K. ( 1995 ) Construction and characterization...
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LETTER: Congenic Mapping of the Type 1 Diabetes Locus, Idd3, to a 780-kb Region of Mouse Chromosome 3: Identification of a Candidate Segment of Ancestral DNA by Haplotype Mapping
- Paul A. Lyons,
- Nicola Armitage,
- Fabio Argentina,
- Paul Denny,
- Natasha J. Hill,
- Christopher J. Lord,
- Mary Beth Wilusz,
- Laurence B. Peterson,
- Linda S. Wicker,
- and John A. Todd
Genome Res. April 1, 2000 10: 446-453; doi:10.1101/gr.10.4.446
...1998 ). Studies in IL2 and IL2 receptor knockout mice have shown that the cytokine plays a nonredundant role during Fas-mediated apoptosis of activated T cells, one of the central processes in immune homeostasis ( Van Parijs et al. 1997 ; Refaeli et al. 1998 ). Variants within the coding or regulatory...
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LETTER: Evolutionarily Conserved Sequences on Human Chromosome 21
- Kelly A. Frazer,
- John B. Sheehan,
- Renee P. Stokowski,
- Xiyin Chen,
- Roya Hosseini,
- Jan-Fang Cheng,
- Stephen P.A. Fodor,
- David R. Cox,
- and Nila Patil
Genome Res. October 1, 2001 11: 1651-1659; doi:10.1101/gr.198201
...chromosome 21. Genomics 74 : 45 – 54 . ↵ Spencer S.D. , Di Marco F. , Hooley J. , Pitts-Meek S. , Bauer M. , Ryan A.M. , Sordat B. , Gibbs V.C. , Aguet M. ( 1998 ) The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J. Exp. Med. 187 : 571 – 578 . ↵ Rubin E.M. , Tall A. ( 2000...
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REVIEW: Defensins and the dynamic genome: What we can learn from structural variation at human chromosome band 8p23.1
- Edward J. Hollox,
- John C.K. Barber,
- Anthony J. Brookes,
- and John A.L. Armour
Genome Res. November 2008 18: 1686-1697; doi:10.1101/gr.080945.108
...to correspond to Class V, with more complex repeat-rich regions flanking it ( Fig. 1 ). At the ends of the beta-defensin genomic repeat unit—perhaps at the shore of the sea of complex olfactory receptor repeats—are FAM90A gene clusters that are on Class III repeats. FAM90A genes are on several other chromosomes...
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LETTER: Genomic Anatomy of a Premier Major Histocompatibility Complex Paralogous Region on Chromosome 1q21–q22
- Takashi Shiina,
- Asako Ando,
- Yumiko Suto,
- Fumio Kasai,
- Atsuko Shigenari,
- Nobusada Takishima,
- Eri Kikkawa,
- Kyoko Iwata,
- Yuko Kuwano,
- Yuka Kitamura,
- Yumiko Matsuzawa,
- Kazumi Sano,
- Masahiro Nogami,
- Hisako Kawata,
- Suyun Li,
- Yasuhito Fukuzumi,
- Masaaki Yamazaki,
- Hiroyuki Tashiro,
- Gen Tamiya,
- Atsushi Kohda,
- Katsuzumi Okumura,
- Toshimichi Ikemura,
- Eiichi Soeda,
- Nobuhisa Mizuki,
- Minoru Kimura,
- Seiamak Bahram,
- and Hidetoshi Inoko
Genome Res. May 1, 2001 11: 789-802; doi:10.1101/gr.175801
.... In summary, we have reported the genomic cloning and sequence analysis of a prototype MHC paralogous region on human chromosome 1q. The identification of a number of immunologically relevant genes and novel olfactory receptor loci lying in close vicinity to the MHC class I CD1 genes help to further define...
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REPORT: Generation and Comparative Analysis of ∼3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome
- Udaya DeSilva,
- Laura Elnitski,
- Jacquelyn R. Idol,
- Johannah L. Doyle,
- Weiniu Gan,
- James W. Thomas,
- Scott Schwartz,
- Nicole L. Dietrich,
- Stephen M. Beckstrom-Sternberg,
- Jennifer C. McDowell,
- Robert W. Blakesley,
- Gerard G. Bouffard,
- Pamela J. Thomas,
- Jeffrey W. Touchman,
- Webb Miller,
- and Eric D. Green
Genome Res. January 1, 2002 12: 3-15; doi:10.1101/gr.214802
...), the region on chromosome 17 containing a cluster of olfactory receptor genes (∼330 kb; Younger et al. 2001 ), a segment on mouse chromosome 16 orthologous to the Down's syndrome critical region (∼470 kb; Pletcher et al. 2001 ), the Fra14A2 / Fhit region (∼600 kb; Shiraishi et al. 2001 ), and the 15 mouse...
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ARTICLE: One-megabase sequence analysis of the human immunoglobulin lambda gene locus.
- K Kawasaki,
- S Minoshima,
- E Nakato,
- K Shibuya,
- A Shintani,
- J L Schmeits,
- J Wang,
- and N Shimizu
Genome Res. March 1997 7: 250-261; doi:10.1101/gr.7.3.250
.... The complete 685-kilobase DNA sequence of the human β T cell receptor locus. Science 272 : 1755 – 1762 . Saitou, N. , Nei. M. Saitou, N. and Nei. M. 1987 . The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4 : 406 – 425 . Sambrook, J., E.F. Fritsch, and T...

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