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Method: A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1
- Dror Hollander,
- Maya Donyo,
- Nir Atias,
- Keren Mekahel,
- Zeev Melamed,
- Sivan Yannai,
- Galit Lev-Maor,
- Asaf Shilo,
- Schraga Schwartz,
- Iris Barshack,
- Roded Sharan,
- and Gil Ast
Genome Res. April 2016 26: 541-553; Published in Advance February 9, 2016, doi:10.1101/gr.193169.115
...A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1 Dror Hollander 1 , Maya Donyo 1 , 7 , Nir Atias 2 , 7 , Keren Mekahel 1 , Zeev Melamed 1 , 8 , Sivan...
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Resource: Benchmark and integration of resources for the estimation of human transcription factor activities
- Luz Garcia-Alonso,
- Christian H. Holland,
- Mahmoud M. Ibrahim,
- Denes Turei,
- and Julio Saez-Rodriguez
Genome Res. August 2019 29: 1363-1375; Published in Advance July 24, 2019, doi:10.1101/gr.240663.118
...-specific regulons inferred from GTEx data perform similarly to inferred consensus regulons (i.e., selecting TF–target interactions detected in several tissues). A reason may be the inherent differences between the gene expression regulatory programs in the samples used to infer the regulatory networks (normal...
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