Searching journal content for articles similar to Bolshoy and Nevo 10 (8): 1185.

Displaying results 1-10 of 6320

For checked items

view abstracts
download to citation manager

Select this article
Research: Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression
- Sudeshna Majumdar,
- Lakshmi Sowjanya Bammidi,
- Hemant C. Naik,
- Avinchal Manhas,
- Runumi Baro,
- Akash Kalita,
- Amlan Jyoti Naskar,
- Sundarraj Nidharshan,
- Girija S. Bariha,
- Dimple Notani,
- and Srimonta Gayen
Genome Res. September 2025 35: 1992-2010; Published in Advance August 6, 2025, doi:10.1101/gr.279822.124
...showing fold changes of Rad21 expression as seen through RNA-seq for D1 ΔXp lines as compared to WT clones and WT EV clones. Right: Genome browser views showing Rad21 expression across the genomic loci for WT clone, WT EV, and D1 ΔXp lines.Deletion of Xist upstream sequence leads to the alterations...
Select this article
Method: Iterative improvement of deep learning models using synthetic regulatory genomics
- André M. Ribeiro-dos-Santos and
- Matthew T. Maurano
Genome Res. November 2025 35: 2539-2549; Published in Advance October 22, 2025, doi:10.1101/gr.280540.125
...and ultimately enable functional classification of regulatory variants identified by population studies.Most genetic associations with human diseases and traits lie within noncoding regulatory DNA (Maurano et al. 2012). Genome-scale methods to analyze the function of noncoding regulatory elements within...
Select this article
Research: Functional genomics analysis of developing zebrafish and human endoderm reveals highly conserved cis-regulatory modules acting during vertebrate organogenesis
- Daniela M. Riley,
- Randa Elsayed,
- Mark D. Walsh,
- Simaran Johal,
- Ying Lin,
- Harry Walton,
- Till Bretschneider,
- Sascha Ott,
- and Andrew C. Nelson
Genome Res. March 4, 2026 ; Published in Advance March 4, 2026, doi:10.1101/gr.280838.125
...discrete regions containing the zebrafish and human HCNE (i5zHCNE and i5hHCNE, respectively). We also tested the upstream accessible region (Enh –3 kb). Each reporter construct also contained the crystallin, alpha a (cryaa) promoter upstream of gfp. This drives GFP expression in the lens of the eye, thus...
Select this article
Method: Taurine pangenome uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle
- Sotiria Milia,
- Alexander S. Leonard,
- Xena Marie Mapel,
- Sandra Milena Bernal Ulloa,
- Cord Drögemüller,
- and Hubert Pausch
Genome Res. April 2025 35: 1041-1052; Published in Advance December 18, 2024, doi:10.1101/gr.279064.124
...Taurine pan uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle Sotiria Milia1,4, Alexander S. Leonard1,4, Xena Marie Mapel1, Sandra Milena Bernal Ulloa2, Cord Drögemüller3 and Hubert Pausch1 1Animal Genomics, ETH Zurich, Zurich 8092, Switzerland...
Select this article
Research: Assessing the readiness of Oxford Nanopore sequencing for clinical genomics applications
- Judith Arres,
- Santosh Elavalli,
- Shalini Behl,
- Daniel Matias Sanchez,
- Ayesha Al Ali,
- Abdelrahman Ahmed Yehia Abdelaziz Saad,
- Azza Attia,
- Cyla Minas,
- Sharika Pariyachery,
- Shariq Ahmed,
- Fatmah Aldhuhoori,
- Nitu Thulasidharan,
- Gurunath Katagi,
- Omar Soliman,
- Shilp Purohit,
- Vinay Kusuma,
- Raony Cardenas,
- Thyago Cardoso,
- Luis F. Paulin,
- Philippe Sanio,
- Joseph Mafofo,
- Haiguo Wu,
- Val Zvereff,
- Albarah El-Khani,
- Fahed Al Marzooqi,
- Tiago R. Magalhães,
- Fritz J. Sedlazeck,
- and Javier Quilez
Genome Res. March 2026 36: 460-471; Published in Advance February 11, 2026, doi:10.1101/gr.280134.124
.... 2025). Therefore, a scalable and accurate workflow must integrate variant-calling methodologies along with upstream basecalling, alignment steps, and quality metrics to ensure high-quality results (Supplemental Note S2).We have consolidated a comprehensive ONT WGS pipeline (Supplemental Fig. S1...
Select this article
Research: Long-read genomics reveal extensive nuclear-specific evolution and allele-specific expression in a dikaryotic fungus
- Rita Tam,
- Mareike Möller,
- Runpeng Luo,
- Zhenyan Luo,
- Ashley Jones,
- Sambasivam Periyannan,
- John P. Rathjen,
- and Benjamin Schwessinger
Genome Res. June 2025 35: 1364-1376; Published in Advance April 11, 2025, doi:10.1101/gr.280359.124
...potential, which may, in turn, promote RNAi-directed silencing to reinforce centromere formation (Balzano and Giunta 2020). Further studies will be required to elucidate such links in Pst.The dikaryotic configuration of Pst prompted us to explore its effect on intraspecific rDNA dynamics under strict...
OPEN ACCESS ARTICLE
Select this article
Method: High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND
- Kehan Lang,
- Chenyang Jia,
- Siyu Li,
- Yi Guo,
- Dingjun Hu,
- and Shengquan Chen
Genome Res. March 26, 2026 ; Published in Advance March 26, 2026, doi:10.1101/gr.281350.125
...development and oligodendrocyte differentiation. (H) Bubble plot showing enriched GO terms among genes with significant pseudotimeassociated promoter-proximal DNA methylation. Lang et al. 8 Genome Research www..org organization, including nervous systemdevelopment, calcium-dependent cell–cell adhesion...
OPEN ACCESS ARTICLE
Select this article
Resource: A systems view on DNA damage response kinetics in Tetrahymena
- Emily Nischwitz,
- Vivien A.C. Schoonenberg,
- Rachel Mullner,
- Albert Fradera-Sola,
- Susanne Zimbelmann,
- Joshua J. Smith,
- and Falk Butter
Genome Res. January 28, 2026 ; Published in Advance January 28, 2026, doi:10.1101/gr.281000.125
...-specific protein response was observed. Nischwitz et al. 2 Genome Research www..org Early transcriptional activity is critical to the DNA damage response To cluster the 8815 dynamic and differentially regulated transcripts, we used self-organizingmaps (SOMs), an unsupervisedmachine learning approach...
Select this article
Review: k-mer approaches for biodiversity genomics
- Katharine M. Jenike,
- Lucía Campos-Domínguez,
- Marilou Boddé,
- José Cerca,
- Christina N. Hodson,
- Michael C. Schatz,
- and Kamil S. Jaron
Genome Res. February 2025 35: 219-230; Published in Advance January 31, 2025, doi:10.1101/gr.279452.124
...other sequence). k-mers are typically used for DNA, but the concept can be applied to RNA and protein sequences as well. Any genomic sequence can be decomposed into a number of consecutive k-mers, and this number will depend on both the length of the sequence (L) and k-mer length (k). For example...
OPEN ACCESS ARTICLE
Select this article
Method: Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease
- Tanner D. Jensen,
- Bohan Ni,
- Chloe M. Reuter,
- John E. Gorzynski,
- Sarah Fazal,
- Devon Bonner,
- Rachel A. Ungar,
- Pagé C. Goddard,
- Archana Raja,
- Euan A. Ashley,
- Jonathan A. Bernstein,
- Stephan Zuchner,
- Undiagnosed Diseases Network,
- Michael D. Greicius,
- Stephen B. Montgomery,
- Michael C. Schatz,
- Matthew T. Wheeler,
- and Alexis Battle
Genome Res. April 2025 35: 914-928; Published in Advance March 20, 2025, doi:10.1101/gr.279323.124
...noncoding variants (row); each dot represent an gene-SV pair. (D) Top positive genomic annotation effect sizes for 100 kb multitissue Watershed-SV model. Seven annotation categories are grouped into region-specific (TSS/upstream Flank, Gene Body, TES/downstream Flank) and region-agnostic features. Region...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Bolshoy and Nevo 10 (8): 1185.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: