Searching journal content for articles similar to Bochner et al. 11 (7): 1246.

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  1. ...High-Throughput Variation Detection and Genotyping Using Microarrays David J. Cutler 1 , 4 , Michael E. Zwick 1 , Minerva M. Carrasquillo 3 , Christopher T. Yohn 1 , Katherine P. Tobin 1 , Carl Kashuk 1 , Debra J. Mathews 3...
  2. ...effective siRNA against any gene. The efficacy of siRNA sequences is monitored by their ability to reduce the expression of cognate target-reporter fusions with easily quantified readouts. Finally, using micro array-based cell transfections, we demonstrate an unlimited potential of this approach in high-throughput...
  3. ...macrophages and single ductal cells inferred to be macrophages (Supplemental File 3). Many of the most significant genes are related to extracellular matrix interactions and leukocyte signaling. These data raise the possibility that intraductal macrophages have a phenotype that is distinct from stromal...
  4. ...genes as significant on-target regulators of RPS6 phosphorylation, and we characterized them with extensive secondary assays probing various arms of the TORC1 pathways, identifying functional relationships among those genes. We conclude that cell-based microarrays are a useful platform for genome...
  5. ...) Oligonucleotide arrays for high-throughput SNPs detection in the MHC class I genes: HLA-B as a model system. Genome Res. 12 : 447 – 457 . ↵ Hacia J.G. , Fan J.B. , Ryder O. , Jin L. , Edgemon K. , Ghandour G. , Mayer R.A. , Sun B. , Hsie L. , Robbins C.M. , et al. ( 1999 ) Determination of ancestral alleles...
  6. ...deletion strains could be arrayed on the permeable membrane within an area of ∼6 cm2. Such cell microarrays would allow high-throughput phenotypic assays (e.g., cell shape, budding pattern, and drug resistance) of gene activities under a variety of conditions. Therefore, cell microarrays should complement...
  7. .... The microarray platform is in a 96-well customizable format for medium-density and high-throughput and up to 250 genes/array ( Lamture et al. 1994 ). In September 1999, Genometrix and Motorola, Inc. agreed to a coexclusive rights agreement to use and commercialize proprietary Genometix electronic DNA chip...
  8. ...-based multiplex analysis of candidate genes reveals two independent and additive genetic risk factors for myocardial infarction in the Finnish population. Hum. Mol. Genet. 7 : 1453 – 1462 . ↵ Pastinen T. , Raitio M. , Lindroos K. , Tainola P. , Peltonen L. , Syvänen A.-C. ( 2000 ) A system for specific, high-throughput...
  9. ...A spatial and temporal map of C. elegans gene expression W. Clay Spencer 1 , 7 , Georg Zeller 2 , 3 , 7 , 8 , Joseph D. Watson 1 , 9 , Stefan R. Henz 3 , Kathie L. Watkins 1 , Rebecca D. McWhirter 1 , Sarah Petersen...
  10. ...is available from the authors on request. Transfection experiments PCR was used to amplify regions corresponding to 680 bp of +29 and 370 bp of +32. These fragments were cloned upstream of the luciferase reporter gene in pGL2 basic (Promega) and assayed in transfection assays. Primer sequences are available...
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