Searching journal content for articles similar to Blencowe et al. 32 (5): 807.

Displaying results 1-10 of 32

For checked items

view abstracts
download to citation manager

Select this article
Research: Gene essentiality in cancer cell lines is modified by the sex chromosomes
- Shahar Shohat,
- Ethel Vol,
- and Sagiv Shifman
Genome Res. November/December 2022 32: 1993-2002; Published in Advance November 23, 2022, doi:10.1101/gr.276488.121
...2010).The two main biological mechanisms that cause human sex differences are gonadal hormone secretions and genes located on the X and Y Chromosomes. There is considerable evidence for sex differences in diseases caused by gonadal hormone secretions (Baron-Cohen et al. 2005; Law et al. 2014; Fuseini...
OPEN ACCESS ARTICLE
Select this article
Resource: Binding profiles for 961 Drosophila and C. elegans transcription factors reveal tissue-specific regulatory relationships
- Michelle Kudron,
- Louis Gevirtzman,
- Alec Victorsen,
- Bridget C. Lear,
- Jiahao Gao,
- Jinrui Xu,
- Swapna Samanta,
- Emily Frink,
- Adri Tran-Pearson,
- Chau Huynh,
- Dionne Vafeados,
- Ann Hammonds,
- William Fisher,
- Martha Wall,
- Greg Wesseling,
- Vanessa Hernandez,
- Zhichun Lin,
- Mary Kasparian,
- Kevin White,
- Ravi Allada,
- Mark Gerstein,
- LaDeana Hillier,
- Susan E. Celniker,
- Valerie Reinke,
- and Robert H. Waterston
Genome Res. December 2024 34: 2319-2334; Published in Advance October 22, 2024, doi:10.1101/gr.279037.124
...and function. Despite the diverse body plans, lifespans, and habitats of different species, the fundamental mechanisms by which TFs control gene regulation are highly conserved. Moreover, mutations in TFs are estimated to contribute to almost one-third of human developmental disorders (Vaquerizas et al. 2009...
Select this article
Resource: Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation
- Kang Du,
- Martin Pippel,
- Susanne Kneitz,
- Romain Feron,
- Irene da Cruz,
- Sylke Winkler,
- Brigitta Wilde,
- Edgar G. Avila Luna,
- Gene Myers,
- Yann Guiguen,
- Constantino Macias Garcia,
- and Manfred Schartl
Genome Res. March 2022 32: 583-594; Published in Advance January 26, 2022, doi:10.1101/gr.275826.121
...on the Y was identified covering 80% of Chromosome 20, allowing some first inferences on the recent origin and a candidate male sex determining gene. Genome-wide transcriptomics uncovered sex-specific differences in brain gene expression with an enrichment for neurosteroidogenesis and testis genes in males...
Select this article
Research: Transposon accumulation at xenobiotic gene family loci in aphids
- Tobias Baril,
- Adam Pym,
- Chris Bass,
- and Alex Hayward
Genome Res. October 2023 33: 1718-1733; Published in Advance October 18, 2023, doi:10.1101/gr.277820.123
...to have contributed to evolvability via myriad mechanisms, including gene amplification and duplication (Remnant et al. 2013; Singh et al. 2020), knockout of a susceptible allele in heterozygous individuals (Panini et al. 2021), increases in detoxification gene expression (Bogwitz et al. 2005; Itokawa et...
OPEN ACCESS ARTICLE
Select this article
Research: The grasshopper genome reveals long-term gene content conservation of the X Chromosome and temporal variation in X Chromosome evolution
- Xinghua Li,
- Judith E. Mank,
- and Liping Ban
Genome Res. July 2024 34: 997-1007; Published in Advance August 5, 2024, doi:10.1101/gr.278794.123
....X Chromosome dosage compensationWe next tested for the presence of complete dosage compensation in L. migratoria (Fig. 4A). In female (XX) grasshoppers, X-linked genes showed higher expression levels than autosomal genes in both somatic and gonad tissues. In male (X0) grasshoppers, X-linked gene expression...
Select this article
Resource: Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish
- Hyung Joo Lee,
- Yiran Hou,
- Ju Heon Maeng,
- Nakul M. Shah,
- Yujie Chen,
- Heather A. Lawson,
- Hongbo Yang,
- Feng Yue,
- and Ting Wang
Genome Res. July 2022 32: 1424-1436; Published in Advance June 1, 2022, doi:10.1101/gr.276052.121
...analysis of zebrafish TEs in the context of gene regulation is lacking. Here, we systematically investigate the epigenomic and transcriptomic landscape of TEs across 11 adult zebrafish tissues using multidimensional sequencing data. We find that TEs contribute substantially to a diverse array of regulatory...
OPEN ACCESS ARTICLE
Select this article
Research: Allelic diversification after transposable element exaptation promoted gsdf as the master sex determining gene of sablefish
- Amaury Herpin,
- Manfred Schartl,
- Alexandra Depincé,
- Yann Guiguen,
- Julien Bobe,
- Aurélie Hua-Van,
- Edward S. Hayman,
- Anna Octavera,
- Goro Yoshizaki,
- Krista M. Nichols,
- Giles W. Goetz,
- and J. Adam Luckenbach
Genome Res. August 2021 31: 1366-1380; Published in Advance June 28, 2021, doi:10.1101/gr.274266.120
.... Further characterization of this locus resulted in identification of the transforming growth factor, beta receptor 1a (tgfbr1a) gene, gonadal somatic cell derived factor (gsdf), as the main candidate for fulfilling the master sex determining (MSD) function. The presence of different X and Y Chromosome...
Select this article
Research: Quantitative analysis of Y-Chromosome gene expression across 36 human tissues
- Alexander K. Godfrey,
- Sahin Naqvi,
- Lukáš Chmátal,
- Joel M. Chick,
- Richard N. Mitchell,
- Steven P. Gygi,
- Helen Skaletsky,
- and David C. Page
Genome Res. June 2020 30: 860-873; Published in Advance May 27, 2020, doi:10.1101/gr.261248.120
..., USA Corresponding author: dcpage@wi.mit.eduAbstractLittle is known about how human Y-Chromosome gene expression directly contributes to differences between XX (female) and XY (male) individuals in nonreproductive tissues. Here, we analyzed quantitative profiles of Y-Chromosome gene expression across...
Select this article
Research: Mapping multitissue regulatory variants reveals a liver-centric coexpression network associated with duck egg-laying performance
- Yang Xi,
- Jingjing Qi,
- Zhao Yang,
- Yutian Zeng,
- Huicong Zhang,
- Qiuyu Tao,
- Mengru Xu,
- Anqi Huang,
- Shenqiang Hu,
- Chunchun Han,
- Lili Bai,
- Jiwei Hu,
- Jiwen Wang,
- Liang Li,
- Lingzhao Fang,
- and Hehe Liu
Genome Res. October 2025 35: 2211-2225; Published in Advance September 10, 2025, doi:10.1101/gr.280345.124
...of the genetic regulatory landscape.The tissue-specific causal regulatory effects of ABCG2 on duck eggshell colorOur GWAS analysis identified four independent loci located on Chromosome 4 (Chr 4) associated with duck eggshell reflectance in the current population, including the previously reported causal gene...
Select this article
LETTER: Tissue-specific expression and regulation of sexually dimorphic genes in mice
- Xia Yang,
- Eric E. Schadt,
- Susanna Wang,
- Hui Wang,
- Arthur P. Arnold,
- Leslie Ingram-Drake,
- Thomas A. Drake,
- and Aldons J. Lusis
Genome Res. August 2006 16: 995-1004; Published in Advance July 6, 2006, doi:10.1101/gr.5217506
...expression of downstream genes ( Krebs et al. 2003 ; Wiwi and Waxman 2004 ; Clodfelter et al. 2006 ). In addition to hormones and receptors, such mediators could include transcription factors and signaling molecules. Recently, the contributions of sex chromosome genes to sex differences in cell phenotype...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Blencowe et al. 32 (5): 807.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: