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  1. ...with human BAC clones. Below is shown gorilla chromosome 4 (GGO 4), syntenic to human chromosomes 5 and 17. The vertical arrow indicates the ∼250 kb genomic duplication, originating from the GGO 19 segment, syntenic to human chromosome, (HSA) 17p12. Smith-Magenis syndrome low-copy repeats, SMS...
  2. ...chromosome 11 region syntenic to the insertional duplication site of the proximal CMT1A-REP to ∼3.5 Kb (np. 41,500–45,034 in RP23–428I5). To determine whether the deletion of this ∼5-Kb fragment was concurrent with the proximal CMT1A-REP segmental duplication and insertional event, we designed PCR primers...
  3. ...in the human has, in turn, its best match against the orthologous mouse gene in the conserved syntenic interval. This one-to-one ratio allows us to define a set of genes that are mammal-specific: a basic kit of genes for creating a basic mammal! Of course, the precise delineation of this set of genes requires...
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