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  1. ...the analysis toward transcription factors whose activity is regulated primarily by the expression level.Recently, a new method, ‘Motif Activity Response Analysis’ (MARA), for prediction of transcription factors involved in gene regulation has been developed. The core function of MARA is to model...
  2. .... Nature 507: 455–461. ↵Azofeifa JG, Dowell RD. 2017. A generative model for the behavior of RNA polymerase. Bioinformatics 33: 227–234. ↵Balwierz PJ, Pachkov M, Arnold P, Gruber AJ, Zavolan M, van Nimwegen E. 2014. ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs. Genome...
  3. ..., Zavolan M, van Nimwegen E. 2014. ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs. Genome Res 24: 869–884. ↵Bass J, Lazar MA. 2016. Circadian time signatures of fitness and disease. Science 354: 994–999. ↵Bhargava A, Herzel H, Ananthasubramaniam B. 2015. Mining for novel...
  4. ...-binding proteins known as transcription factors (TFs). Signaling cascades often change the activity levels of specific TFs—the extent to which they exert their regulatory potential on their target genes—via mechanisms that affect TFs’ abundance, localization, noncovalent interactions, or covalent modifications...
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