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Research: Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes
- Hamish W. King,
- Nadezda A. Fursova,
- Neil P. Blackledge,
- and Robert J. Klose
Genome Res. October 2018 28: 1494-1507; Published in Advance August 28, 2018, doi:10.1101/gr.237180.118
...group (PcG) proteins play central roles in developmental gene regulation. This diverse group of proteins form large multiprotein complexes that bind gene regulatory elements and modify chromatin to establish what is thought to be a transcriptionally repressive chromatin state (Müller and Verrijzer 2009...
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Research: Coassembly of REST and its cofactors at sites of gene repression in embryonic stem cells
- Hong-Bing Yu,
- Rory Johnson,
- Galih Kunarso,
- and Lawrence W. Stanton
Genome Res. August 2011 21: 1284-1293; Published in Advance June 1, 2011, doi:10.1101/gr.114488.110
...(H3K4me3), repressed chromatin (H3K9me3), transcriptional elongation (H3K36me3), and heterochromatin (H4K20me3) (Mikkelsen et al. 2007; Ku et al. 2008; Meissner et al. 2008). We also included a map of the nucleosome remodeling factor SMARCA4, previously shown by biochemical methods to be recruited...

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