Searching journal content for articles similar to Allen et al. 29 (3): 464.

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  1. Method: Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing
    • Kepin Wang,
    • Qin Jin,
    • Degong Ruan,
    • Yi Yang,
    • Qishuai Liu,
    • Han Wu,
    • Zhiwei Zhou,
    • Zhen Ouyang,
    • Zhaoming Liu,
    • Yu Zhao,
    • Bentian Zhao,
    • Quanjun Zhang,
    • Jiangyun Peng,
    • Chengdan Lai,
    • Nana Fan,
    • Yanhui Liang,
    • Ting Lan,
    • Nan Li,
    • Xiaoshan Wang,
    • Xinlu Wang,
    • Yong Fan,
    • Pieter A. Doevendans,
    • Joost P.G. Sluijter,
    • Pentao Liu,
    • Xiaoping Li,
    • and Liangxue Lai
    Genome Res. December 2017 27: 2061-2071; Published in Advance November 16, 2017, doi:10.1101/gr.222521.117
    ...viral vector delivery and in vivo CRISPR/Cas9-mediated somatic editing. Genes Dev 29: 1576–1585. ↵Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, et al. 2017. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma...
  2. Research: Integration site-dependent HIV-1 promoter activity shapes host chromatin conformation
    • Jack A. Collora and
    • Ya-Chi Ho
    Genome Res. June 9, 2023 gr.277698.123; Published in Advance June 9, 2023, doi:10.1101/gr.277698.123
    ...the 22 impact of HIV-1 promoter activity on host chromatin accessibility downstream of the integration site, we used 23 sgRNA targeting HIV-1 promoter versus nontargeting controls (NT) with CRISPR-activation (CRISPRa) and 24 CRISPR-inhibition (CRISPRi) cell line clones. We examined whether activation...
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  3. Perspective: Genomic approaches for understanding the genetics of complex disease
    • William L. Lowe, Jr. and
    • Timothy E. Reddy
    Genome Res. October 2015 25: 1432-1441; doi:10.1101/gr.190603.115
    ...for identifying individual regulatory variants that contribute to phenotype (Musunuru et al. 2010; Feng et al. 2013; Fogarty et al. 2014; Stadhouders et al. 2014; Guo et al. 2015). Themajor drawback to standard reporter assay systems for genetic screens is the throughput. Because readout is limited to a single...
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