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Method: Strain-level metagenomic profiling using pangenome graphs with PanTax
- Wenhai Zhang,
- Yuansheng Liu,
- Guangyi Li,
- Jialu Xu,
- Enlian Chen,
- Alexander Schönhuth,
- and Xiao Luo
Genome Res. February 2026 36: 405-420; Published in Advance January 14, 2026, doi:10.1101/gr.280858.125
...that are indicative of species. For example, whereas the 16S rRNA sequence is commonly used in some microbiome analysis methods due to its high conservation (Edgar 2018), tools like MetaPhlAn4 and mOTUs rely on a broader set of specific taxon-specific markers. Although these methods are computationally efficient...
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Editorial: RECOMB 2025 Special Issue
- Sriram Sankararaman and
- Bonnie Berger
Genome Res. December 2025 35: v-vi; doi:10.1101/gr.281664.125
...), as described at http://creativecommons.org/licenses/by-nc/4.0/ . References ↵ Ahmed O , Boucher C , Langmead B . 2025 . Robust 16S rRNA classification based on a compressed LCA index . Genome Res (this issue) 35 : 2650 – 2660 . doi: 10.1101/gr.279846.124 ↵ Al-Abri R , Gürsoy G . 2025 . Estimating the size...

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