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Thomas A. Down
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11
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Research
:
Extreme HOT regions are CpG-dense promoters in
C. elegans
and humans
Ron A.-J. Chen
,
Przemyslaw Stempor
,
Thomas A. Down
,
Eva Zeiser
,
Sky K. Feuer
,
and
Julie Ahringer
Genome Res.
July 2014
24
:
1138
-
1146
;
Published in Advance
March 20, 2014
,
doi:
10.1101/gr.161992.113
Abstract
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Resource
:
The landscape of RNA polymerase II transcription initiation in
C. elegans
reveals promoter and enhancer architectures
Ron A.-J. Chen
,
Thomas A. Down
,
Przemyslaw Stempor
,
Q. Brent Chen
,
Thea A. Egelhofer
,
LaDeana W. Hillier
,
Tess E. Jeffers
,
and
Julie Ahringer
Genome Res.
August 2013
23
:
1339
-
1347
;
Published in Advance
April 2, 2013
,
doi:
10.1101/gr.153668.112
Abstract
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Research
:
A functional methylome map of ulcerative colitis
Robert Häsler
,
Zhe Feng
,
Liselotte Bäckdahl
,
Martina E. Spehlmann
,
Andre Franke
,
Andrew Teschendorff
,
Vardhman K. Rakyan
,
Thomas A. Down
,
Gareth A. Wilson
,
Andrew Feber
,
Stephan Beck
,
Stefan Schreiber
,
and
Philip Rosenstiel
Genome Res.
November 2012
22
:
2130
-
2137
;
Published in Advance
July 23, 2012
,
doi:
10.1101/gr.138347.112
Abstract
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Research
:
Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
Huriya Beyan
,
Thomas A. Down
,
Sreeram V. Ramagopalan
,
Kristina Uvebrant
,
Anita Nilsson
,
Michelle L. Holland
,
Carolina Gemma
,
Gavin Giovannoni
,
Bernhard O. Boehm
,
George C. Ebers
,
Åke Lernmark
,
Corrado M. Cilio
,
R. David Leslie
,
and
Vardhman K. Rakyan
Genome Res.
November 2012
22
:
2138
-
2145
;
Published in Advance
August 23, 2012
,
doi:
10.1101/gr.134304.111
Abstract
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Research
:
Comparative methylomics reveals gene-body H3K36me3 in
Drosophila
predicts DNA methylation and CpG landscapes in other invertebrates
Lisa Nanty
,
Guillermo Carbajosa
,
Graham A. Heap
,
Francis Ratnieks
,
David A. van Heel
,
Thomas A. Down
,
and
Vardhman K. Rakyan
Genome Res.
November 2011
21
:
1841
-
1850
;
Published in Advance
September 22, 2011
,
doi:
10.1101/gr.121640.111
Abstract
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Research
:
Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors
Andrew Feber
,
Gareth A. Wilson
,
Lu Zhang
,
Nadege Presneau
,
Bernadine Idowu
,
Thomas A. Down
,
Vardhman K. Rakyan
,
Luke A. Noon
,
Alison C. Lloyd
,
Elia Stupka
,
Vassia Schiza
,
Andrew E. Teschendorff
,
Gary P. Schroth
,
Adrienne Flanagan
,
and
Stephan Beck
Genome Res.
April 2011
21
:
515
-
524
;
Published in Advance
February 1, 2011
,
doi:
10.1101/gr.109678.110
Abstract
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Research
:
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
Vardhman K. Rakyan
,
Thomas A. Down
,
Siarhei Maslau
,
Toby Andrew
,
Tsun-Po Yang
,
Huriya Beyan
,
Pamela Whittaker
,
Owen T. McCann
,
Sarah Finer
,
Ana M. Valdes
,
R. David Leslie
,
Panogiotis Deloukas
,
and
Timothy D. Spector
Genome Res.
April 2010
20
:
434
-
439
;
Published in Advance
March 10, 2010
,
doi:
10.1101/gr.103101.109
Abstract
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Letter
:
Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level
Alexander W. Bruce
,
Andrés J. López-Contreras
,
Paul Flicek
,
Thomas A. Down
,
Pawandeep Dhami
,
Shane C. Dillon
,
Christoph M. Koch
,
Cordelia F. Langford
,
Ian Dunham
,
Robert M. Andrews
,
and
David Vetrie
Genome Res.
June 2009
19
:
994
-
1005
;
Published in Advance
April 28, 2009
,
doi:
10.1101/gr.089086.108
Abstract
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RESOURCE
:
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)
Vardhman K. Rakyan
,
Thomas A. Down
,
Natalie P. Thorne
,
Paul Flicek
,
Eugene Kulesha
,
Stefan Gräf
,
Eleni M. Tomazou
,
Liselotte Bäckdahl
,
Nathan Johnson
,
Marlis Herberth
,
Kevin L. Howe
,
David K. Jackson
,
Marcos M. Miretti
,
Heike Fiegler
,
John C. Marioni
,
Ewan Birney
,
Tim J.P. Hubbard
,
Nigel P. Carter
,
Simon Tavaré
,
and
Stephan Beck
Genome Res.
September 2008
18
:
1518
-
1529
;
Published in Advance
June 24, 2008
,
doi:
10.1101/gr.077479.108
Abstract
Full Text
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ENSEMBL Special
:
An Overview of Ensembl
Ewan Birney
,
T. Daniel Andrews
,
Paul Bevan
,
Mario Caccamo
,
Yuan Chen
,
Laura Clarke
,
Guy Coates
,
James Cuff
,
Val Curwen
,
Tim Cutts
,
Thomas Down
,
Eduardo Eyras
,
Xose M. Fernandez-Suarez
,
Paul Gane
,
Brian Gibbins
,
James Gilbert
,
Martin Hammond
,
Hans-Rudolf Hotz
,
Vivek Iyer
,
Kerstin Jekosch
,
Andreas Kahari
,
Arek Kasprzyk
,
Damian Keefe
,
Stephen Keenan
,
Heikki Lehvaslaiho
,
Graham McVicker
,
Craig Melsopp
,
Patrick Meidl
,
Emmanuel Mongin
,
Roger Pettett
,
Simon Potter
,
Glenn Proctor
,
Mark Rae
,
Steve Searle
,
Guy Slater
,
Damian Smedley
,
James Smith
,
Will Spooner
,
Arne Stabenau
,
James Stalker
,
Roy Storey
,
Abel Ureta-Vidal
,
K. Cara Woodwark
,
Graham Cameron
,
Richard Durbin
,
Anthony Cox
,
Tim Hubbard
,
and
Michele Clamp
Genome Res.
May 2004
14
:
925
-
928
;
Published in Advance
April 12, 2004
,
doi:
10.1101/gr.1860604
Abstract
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