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Method

Optical genome mapping identifies clinically relevant somatic structural variation in epilepsy-affected brain tissue

  • Anthony R Miller
  • James J Anderson
  • Maria Elena Hernandez Gonzalez
  • Lakshmi Prakruthi Rao Venkata
  • Eileen Stonerock
  • Lauren Mashburn-Warren Allison Daley Jeffrey Leonard Jonathan Pindrik Ammar Shaikhouni Daniel R Boue Diana L Thomas Christopher R Pierson Adam P Ostendorf
  • ... [+9 authors] ...,
  • Elaine R Mardis
  • Daniel C Koboldt
  • Katherine E Miller
  • Tracy A Bedrosian
  • First Published October 1, 2026
Method

Fast and accurate construction of multiple sequence alignments from protein language embeddings with ARIES

  • Minh Hoang
  • Isabel Armour-Garb
  • Mona Singh
  • First Published October 1, 2026
Research

Meso-scale spatial analysis of papilloma formation and clonal expansion in cancerized skin

  • Veronica F Busa
  • Mikaela Behm
  • Pablo Baeza-Centurion
  • Jusung Lee
  • Marie-Luise Koch
  • Meike Schopp Daniela Sohn
  • ... [+2 authors] ...,
  • Stefania Del Prete
  • Michaela Frye
  • Angela Goncalves
  • Duncan Odom
  • First Published October 1, 2026
Method

Scaling coalescent-based species tree inference to 100,000 taxa with STELAR-X

  • Anik Saha
  • Md Shamsuzzoha Bayzid
  • First Published October 1, 2026
Corrigendum

Corrigendum: Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing

  • Shilin Zhang
  • Yichen Wang
  • Lin Jia
  • Xue Wen
  • Zhonghua Du
  • Cong Wang Yajing Hao Dehai Yu Lei Zhou Naifei Chen Jingcheng Chen Huiling Chen Hui Zhang Ilkay Celik Günhan Gülsoy Jianjun Luo Baoming Qin Xueling Cui Zhonghui Liu Songling Zhang Miguel A. Esteban Ferhat Ay Wei Xu Runsheng Chen
  • ... [+19 authors] ...,
  • Wei Li
  • Andrew R. Hoffman
  • Ji-Fan Hu
  • Jiuwei Cui
  • First Published October 1, 2026
Research

Dissecting functional regulatory convergence over 160 million years of therian evolution

  • Navya Shukla
  • Laura Emily Cook
  • Davide Maria Vespasiani
  • Andrew J. Pask
  • Irene Gallego Romero
  • First Published September 23, 2026
Method

Viral haplotype reconstruction from long reads with virCHap

  • Yun Gao
  • Bingqiang Liu
  • Guojun Li
  • Ting Yu
  • First Published September 23, 2026
Method

Multilevel ensemble for genome-wide prediction of cell-specific G-quadruplexes utilizing transformed sequences and enhanced chromatin accessibility with G4Beacon2

  • Tiantong Tao
  • Rongxin Zhang
  • Huiling Shu
  • Yuqing Ma
  • Zhuofan Zhang
  • Jing Tu
  • Xiao Sun
  • First Published September 22, 2026
Method

Decoding cell division history and lineage-resolved phenotypic patterns from single-cell barcode and transcriptomic data

  • Xiaochen Yu
  • Zihao Wang
  • Zhenquan Zhang
  • Yuxin Wang
  • Yuting Lin
  • Lijun Hong
  • ... [+1 authors] ...,
  • Xiaoshu Chen
  • Xionglei He
  • Jian-Rong Yang
  • Jiajun Zhang
  • First Published September 21, 2026
Research

Spatial genome organization in nematodes with programmed DNA elimination

  • James R Simmons
  • Tianchun Xue
  • Rachel Patton McCord
  • Jianbin Wang
  • First Published September 21, 2026
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