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J Chen
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Displaying results 1-10 of
47
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Method
:
Restoring the potency of neutralizing antibody via guided hypermutation with hyper-antibody editor
Yuhong Wang
,
Yuefeng Guo
,
Qiuyu Lu
,
Xinyi Liu
,
Haoqi Xu
,
Jiayi Chen
,
Ruiqi Pi
,
Shaopeng Yuan
,
Ziting Yang
,
Rusen Lu
,
Fei-Long Meng
,
Tingting Gan
,
and
Jiazhi Hu
Genome Res.
March 19, 2026
gr.281396.125
;
Published in Advance
March 19, 2026
,
doi:
10.1101/gr.281396.125
Abstract
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Method
:
scSHEFT enables multiomics label transfer from scRNA-seq to scATAC-seq through dual alignment
Zhitao Huang
,
Ruiqing Zheng
,
Pengzhen Jia
,
Xuhua Yan
,
Jinmiao Chen
,
and
Min Li
Genome Res.
February 2026
36
:
387
-
396
;
Published in Advance
January 20, 2026
,
doi:
10.1101/gr.280410.125
Abstract
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Method
:
Polyomino reconstructs spatial transcriptomic profiles with single-cell resolution via a region-allocation method
Quanyou Cai
,
Lihui Lin
,
Xin Liu
,
and
Jiekai Chen
Genome Res.
November 2025
35
:
2513
-
2526
;
Published in Advance
October 22, 2025
,
doi:
10.1101/gr.280532.125
Abstract
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Method
:
Efficient integration of spatial omics data for joint domain detection, matching, and alignment with stMSA
Han Shu
,
Jing Chen
,
Chang Xu
,
Jialu Hu
,
Yongtian Wang
,
Jiajie Peng
,
Qinghua Jiang
,
Xuequn Shang
,
and
Tao Wang
Genome Res.
October 2025
35
:
2285
-
2299
;
Published in Advance
August 14, 2025
,
doi:
10.1101/gr.280584.125
Abstract
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Research
:
Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection
Jian-Hai Chen
,
Patrick Landback
,
Deanna Arsala
,
Alexander Guzzetta
,
Shengqian Xia
,
Jared Atlas
,
Dylan Sosa
,
Yong E. Zhang
,
Jingqiu Cheng
,
Bairong Shen
,
and
Manyuan Long
Genome Res.
March 2025
35
:
379
-
392
;
Published in Advance
February 14, 2025
,
doi:
10.1101/gr.279498.124
Abstract
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Research
:
Hierarchical architecture of neo-sex chromosomes and accelerated adaptive evolution in tortricid moths
Fangyuan Yang
,
Li-Jun Cao
,
Petr Nguyen
,
Zhong-Zheng Ma
,
Jin-Cui Chen
,
Wei Song
,
and
Shu-Jun Wei
Genome Res.
January 2025
35
:
66
-
77
;
Published in Advance
January 6, 2025
,
doi:
10.1101/gr.279569.124
Abstract
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Resource
:
Chromosome-level subgenome-aware de novo assembly provides insight into
Saccharomyces bayanus
genome divergence after hybridization
Cory Gardner
,
Junhao Chen
,
Christina Hadfield
,
Zhaolian Lu
,
David Debruin
,
Yu Zhan
,
Maureen J. Donlin
,
Tae-Hyuk Ahn
,
and
Zhenguo Lin
Genome Res.
November 2024
34
:
2133
-
2146
;
Published in Advance
September 17, 2024
,
doi:
10.1101/gr.279364.124
Abstract
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Research
:
MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain
Jiayang Chen
,
Nicole A. Fuhler
,
Kevin K. Noguchi
,
and
Joseph D. Dougherty
Genome Res.
April 2023
33
:
541
-
556
;
Published in Advance
April 26, 2023
,
doi:
10.1101/gr.277413.122
Abstract
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Method
:
Classification and clustering of RNA crosslink-ligation data reveal complex structures and homodimers
Minjie Zhang
,
Irena T. Hwang
,
Kongpan Li
,
Jianhui Bai
,
Jian-Fu Chen
,
Tsachy Weissman
,
James Y. Zou
,
and
Zhipeng Lu
Genome Res.
May 2022
32
:
968
-
985
;
Published in Advance
March 24, 2022
,
doi:
10.1101/gr.275979.121
Abstract
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Method
:
Antibody-free profiling of transcription factor occupancy during early embryogenesis by FitCUT&RUN
Xiangxiu Wang
,
Wen Wang
,
Yiman Wang
,
Jia Chen
,
Guifen Liu
,
and
Yong Zhang
Genome Res.
February 2022
32
:
378
-
388
;
Published in Advance
December 29, 2021
,
doi:
10.1101/gr.275837.121
Abstract
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Single-cell gene signature scoring
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Short tandem repeat genotyping using long reads
Spectral component approach for recent population structure
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